RESCU (Methodology) CORE: Core unit personnel will be involved in providing each of the following four major services: project design, statistical support, Framingham/Beijing/MOST and OAI epidemiologic analyses and administration. Although these services can be considered separately for ease of presentation, they in fact represent a rich network of integrated functions that will contribute to MCRC performance in a number of ways. First, the centralization of these services helps to integrate the multiple research projects of the Center and will also serve to facilitate their administration. Second, the core service functions will provide supplemental support for projects in epidemiology and other clinical research funded through this MCRC proposal and for a number of other projects that are or will be funded from other sources. This core unit already provides substantial research support for multiple externally funded projects (e.g. three center grants, four R-01/U-01's) and will continue to do so during the next 5 year cycle. RESCU will also provide critical start up support for new projects that evolve during the grant cycle. Third, the core will provide services to other research activities including basic and clinical research projects such as those in vasculitis and scleroderma. Fourth, core funds will enable our staff to continue their consultative support of researchers at other arthritis units. The core unit arrangement will create a network of resources that extends the functions of staff beyond their specific project assignments and facilitates the efficient use of staff time. Two key features of this central resources are the shared office space of members of this support unit which leads them to frequent interactions, and the weekly staff meetings (RESCU meetings) in which ongoing and proposed research projects are critically evaluated. The continuation of this successful core unit will thus provide a set of centralized and shared resources that will enhance our productivity in an area of special Center emphasis and that will contribute to a resource in support of other arthritis investigators who need design and analysis advice.

Public Health Relevance

The RESCU core is the heart of this MCRC. Composed of a group of multidisciplinary investigators who work in close geographic proximity, this group meets together once a week to review and critique a large portfolio of diverse studies and provide methodologic assistance for research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR047785-12
Application #
8511566
Study Section
Special Emphasis Panel (ZAR1-KM)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
12
Fiscal Year
2013
Total Cost
$538,157
Indirect Cost
$241,087
Name
Boston University
Department
Type
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
White, Daniel K; Neogi, Tuhina; Zhang, Yuqing et al. (2017) Association of Slow Gait Speed With Trajectories of Worsening Depressive Symptoms in Knee Osteoarthritis: An Observational Study. Arthritis Care Res (Hoboken) 69:209-215
Zhang, Yuqing; Lu, Na; Peloquin, Christine et al. (2017) Improved survival in rheumatoid arthritis: a general population-based cohort study. Ann Rheum Dis 76:408-413
Vargas-Santos, Ana Beatriz; Neogi, Tuhina (2017) Management of Gout and Hyperuricemia in CKD. Am J Kidney Dis 70:422-439
Widjajahakim, Rafael; Roux, Michael; Jarraya, Mohamed et al. (2017) Relationship of Trochlear Morphology and Patellofemoral Joint Alignment to Superolateral Hoffa Fat Pad Edema on MR Images in Individuals with or at Risk for Osteoarthritis of the Knee: The MOST Study. Radiology 284:806-814
Unizony, Sebastian; Lu, Na; Tomasson, Gunnar et al. (2017) Temporal Trends of Venous Thromboembolism Risk Before and After Diagnosis of Giant Cell Arteritis. Arthritis Rheumatol 69:176-184
Culvenor, Adam G; Felson, David T; Niu, Jingbo et al. (2017) Thigh Muscle Specific-Strength and the Risk of Incident Knee Osteoarthritis: The Influence of Sex and Greater Body Mass Index. Arthritis Care Res (Hoboken) 69:1266-1270
Misra, Devyani; Lu, Na; Felson, David et al. (2017) Does knee replacement surgery for osteoarthritis improve survival? The jury is still out. Ann Rheum Dis 76:140-146
Misra, Devyani; Peloquin, Christine; Kiel, Douglas P et al. (2017) Intermittent Nitrate Use and Risk of Hip Fracture. Am J Med 130:229.e15-229.e20
Vaughan, Molly W; Felson, David T; LaValley, Michael P et al. (2017) Perceived Community Environmental Factors and Risk of Five-Year Participation Restriction Among Older Adults With or at Risk of Knee Osteoarthritis. Arthritis Care Res (Hoboken) 69:952-958
Strand, Mette P; Neogi, Tuhina; Niu, Jingbo et al. (2017) No association between metabolic syndrome and radiographic hand osteoarthritis: Data from the Framingham study. Arthritis Care Res (Hoboken) :

Showing the most recent 10 out of 402 publications