The established mission of the Methodology Core for the UAB Multidisciplinary Clinical Research Center (MCRC) is to develop and provide state of the art methodology and methodological education in the collaborative support of clinical and translational research in arthritis and musculoskeletal disease (MSD) at the local, regional, national, and international level. Toward this goal, the Methodology Core will continue to provide the statistical, epidemiological, outcomes research, statistical genetics, economics/cost effectiveness, and bioinformatics leadership and expertise required to develop and perform cutting-edge clinical research in arthritis and MSD as it pursues four broad goals are to: I. Support the design, data collection, management, and analytic efforts of the MCRC projects. II. Nurture original research in methodology applicable to clinical research in arthritis and MSD. III. Develop new investigators in the area of arthritis and MSD research. IV. Provide methodology seminars, workshops, and mini-courses to introduce the newest methodological approaches to the MCRC research base.

Public Health Relevance

of this core is defined by the core's mission to assist in the design, data collection, analysis and general oversight of the proposed projects, to develop new research projects from within the research base, and provide educational opportinities to the members of the research base.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Comprehensive Center (P60)
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Special Emphasis Panel (ZAR1-KM)
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University of Alabama Birmingham
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Hartman, Holly; Wang, Yuge; Schroeder Jr, Harry W et al. (2018) Absorbance summation: A novel approach for analyzing high-throughput ELISA data in the absence of a standard. PLoS One 13:e0198528
Stoll, Matthew L; Pierce, M Kathy; Watkins, Jordan A et al. (2018) Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis. Genes Immun :
Curtis, Jeffrey R; Chen, Lang; Danila, Maria I et al. (2018) Routine Use of Quantitative Disease Activity Measurements among US Rheumatologists: Implications for Treat-to-target Management Strategies in Rheumatoid Arthritis. J Rheumatol 45:40-44
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Curtis, Jeffrey R; Chen, Lang; Greenberg, Jeffrey D et al. (2017) The clinical status and economic savings associated with remission among patients with rheumatoid arthritis: leveraging linked registry and claims data for synergistic insights. Pharmacoepidemiol Drug Saf 26:310-319
Yen, Po-Yin; Lara, Barbara; Lopetegui, Marcelo et al. (2016) Usability and Workflow Evaluation of ""RhEumAtic Disease activitY"" (READY). A Mobile Application for Rheumatology Patients and Providers. Appl Clin Inform 7:1007-1024
Stoll, Matthew L; Cron, Randy Q (2016) The microbiota in pediatric rheumatic disease: epiphenomenon or therapeutic target? Curr Opin Rheumatol 28:537-43

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