This proposal seeks the continuation of the University of Chicago Diabetes Research and Training Center (DRTC). The Center is an interdepartmental and interinstitutional cooperative endeavor involving investigators from the University of Chicago, Illinois Institute of Technology, Loyola University Chicago School of Nursing, Northern Illinois University, Northwestern University Feinberg School of Medicine and the University of Illinois at Chicago Schools of Medicine and Nursing with differing scientific backgrounds, yet sharing a common interest in diabetes and related research.
The aims of the Center are: 1. To foster collaborative, multidisciplinary diabetes and endocrinology research in a supportive environment;2. To enhance the clinical and basic research capabilities of established diabetes investigators;3. To encourage investigators not involved in diabetes research to pursue problems related to diabetes and endocrinology;4. To speed the transfer of advances in basic biomedical and genetic research to the clinical arena whey they may be applied to the diagnosis and treatment of persons with diabetes;and 5. To inform others in both professional and lay settings of the accomplishments, opportunities and advances in diabetes research and training. This application consists of three sections: Section 1 - Overview;Section 2 - Administrative component;and Section 3 - Biomedical Research Component (Research base, Biomedical research cores (Islet Cell Biology, Molecular Biology and Genetics, Ligand Assay, Physiology, and Animal Models), Prevention and Control core, Pilot and Feasibility Program, and Enrichment Program). It also contains an Appendix.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
5P60DK020595-35
Application #
8217275
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O1))
Program Officer
Hyde, James F
Project Start
1996-12-01
Project End
2013-02-28
Budget Start
2012-02-01
Budget End
2013-02-28
Support Year
35
Fiscal Year
2012
Total Cost
$1,331,867
Indirect Cost
$464,201
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Birken, Sarah A; Lee, Shoou-Yih Daniel; Weiner, Bryan J et al. (2015) From strategy to action: how top managers' support increases middle managers' commitment to innovation implementation in health care organizations. Health Care Manage Rev 40:159-68
Makinen, Marvin W; Salehitazangi, Marzieh (2014) The Structural Basis of Action of Vanadyl (VO(2+)) Chelates in Cells. Coord Chem Rev 279:1-22
Kirkley, Andrew G; Sargis, Robert M (2014) Environmental endocrine disruption of energy metabolism and cardiovascular risk. Curr Diab Rep 14:494
Park, Soo-Young; Ludwig, Michael Z; Tamarina, Natalia A et al. (2014) Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics 196:539-55
Raffel, Katie E; Goddu, Anna P; Peek, Monica E (2014) "I Kept Coming for the Love": Enhancing the Retention of Urban African Americans in Diabetes Education. Diabetes Educ 40:351-360
Guyon, A; Balbo, M; Morselli, L L et al. (2014) Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men. J Clin Endocrinol Metab 99:2861-8
Copinschi, Georges; Leproult, Rachel; Spiegel, Karine (2014) The important role of sleep in metabolism. Front Horm Res 42:59-72
Grimaldi, Daniela; Beccuti, Guglielmo; Touma, Carol et al. (2014) Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications. Diabetes Care 37:355-63
Liew, Chong Wee; Assmann, Anke; Templin, Andrew T et al. (2014) Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ? cells. Proc Natl Acad Sci U S A 111:E2319-28
Menting, John G; Yang, Yanwu; Chan, Shu Jin et al. (2014) Protective hinge in insulin opens to enable its receptor engagement. Proc Natl Acad Sci U S A 111:E3395-404

Showing the most recent 10 out of 724 publications