The overall goal of the Metrics & Health Services Research (MHSR) Core of the DRTC is to provide the expertise and infrastructure required to create new knowledge in the prevention and control of diabetes and cardiometabolic disease; and effectively and reproducibly implement developed prevention and control strategies. Arising from over-arching programmatic needs at the national level that are clearly perceived by the DRTC's research base, the MHSR Core's 5 Specific Aims are to provide: (1) Access to state-of-the-art measurement tools in the domains relevant to diabetes prevention and control research, e.g. assessments of diet and nutrition, physical activity, behavioral/psychosocial factors, health related quality of life, and healthcare quality; (2) Design, data management, and analytic support, including econometric capacity; (3) Access to large pre-existing national datasets for secondary data analyses to test hypotheses in the prevention and control of diabetes and cardiometabolic disease; (4) Development of methodological innovations in diabetes prevention and control research; and (5) Effective implementation and dissemination support for maximizing the knowledge produced by the DRTC research base. The MHSR Core is directed by two national leaders in health services research (Kiefe) and diabetes epidemiology (Lewis), and will contain three service units, Psychosocial/Behavioral, Design/Data Management & Analysis, and Health Services Research. Core services are based on the expressed needs of funded DRTC Members, and methods will rely on state-of-the-art measurement approaches with a very high priority given to data quality control. A well-defined reporting structure, clear system of prioritization, and pre-defined chargeback system will ensure the Core's viability. State-of-the-art tools in health services and epidemiology research have tremendous potential to advance diabetes prevention and control, and the NIH Roadmap agenda of translation from bench to bedside to community. The MHSR Core will make cutting-edge expertise in these areas newly available to the DRTC research base, expanding the scientific armamentarium and capacity of diabetes researchers at UAB.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
5P60DK079626-05
Application #
8448796
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O1))
Project Start
Project End
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
5
Fiscal Year
2012
Total Cost
$188,719
Indirect Cost
$58,568
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Mohler 3rd, Emile R; Ellenberg, Susan S; Lewis, Cora E et al. (2018) The Effect of Testosterone on Cardiovascular Biomarkers in the Testosterone Trials. J Clin Endocrinol Metab 103:681-688
Hunter, Gary R; Bryan, David R; Borges, Juliano H et al. (2018) Racial Differences in Relative Skeletal Muscle Mass Loss During Diet-Induced Weight Loss in Women. Obesity (Silver Spring) 26:1255-1260
Wingo, Brooks C; Barry, Valene Garr; Ellis, Amy C et al. (2018) Comparison of segmental body composition estimated by bioelectrical impedance analysis and dual-energy X-ray absorptiometry. Clin Nutr ESPEN 28:141-147
Hunter, Gary R; Plaisance, Eric P; Carter, Stephen J et al. (2018) Why intensity is not a bad word: Optimizing health status at any age. Clin Nutr 37:56-60
Engle, Staci E; Antonellis, Patrick J; Whitehouse, Logan S et al. (2018) A CreER mouse to study melanin concentrating hormone signaling in the developing brain. Genesis 56:e23217
Hunter, Gary R; Fisher, Gordon; Bryan, David R et al. (2018) Divergent Blood Pressure Response After High-Intensity Interval Exercise: A Signal of Delayed Recovery? J Strength Cond Res 32:3004-3010
Snyder, Peter J; Bhasin, Shalender; Cunningham, Glenn R et al. (2018) Lessons From the Testosterone Trials. Endocr Rev 39:369-386
Kang, Minsung; Liu, Xiaobing; Fu, Yuchang et al. (2018) Improved systemic metabolism and adipocyte biology in miR-150 knockout mice. Metabolism 83:139-148
Jo, SeongHo; Chen, Junqin; Xu, Guanlan et al. (2018) miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function. Diabetes 67:256-264
Ingram, K H; Hunter, G R; James, J F et al. (2017) Central fat accretion and insulin sensitivity: differential relationships in parous and nulliparous women. Int J Obes (Lond) 41:1214-1217

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