The overall goal of the Metrics & Health Services Research (MHSR) Core of the DRTC is to provide the expertise and infrastructure required to create new knowledge in the prevention and control of diabetes and cardiometabolic disease; and effectively and reproducibly implement developed prevention and control strategies. Arising from over-arching programmatic needs at the national level that are clearly perceived by the DRTC's research base, the MHSR Core's 5 Specific Aims are to provide: (1) Access to state-of-the-art measurement tools in the domains relevant to diabetes prevention and control research, e.g. assessments of diet and nutrition, physical activity, behavioral/psychosocial factors, health related quality of life, and healthcare quality; (2) Design, data management, and analytic support, including econometric capacity; (3) Access to large pre-existing national datasets for secondary data analyses to test hypotheses in the prevention and control of diabetes and cardiometabolic disease; (4) Development of methodological innovations in diabetes prevention and control research; and (5) Effective implementation and dissemination support for maximizing the knowledge produced by the DRTC research base. The MHSR Core is directed by two national leaders in health services research (Kiefe) and diabetes epidemiology (Lewis), and will contain three service units, Psychosocial/Behavioral, Design/Data Management & Analysis, and Health Services Research. Core services are based on the expressed needs of funded DRTC Members, and methods will rely on state-of-the-art measurement approaches with a very high priority given to data quality control. A well-defined reporting structure, clear system of prioritization, and pre-defined chargeback system will ensure the Core's viability. State-of-the-art tools in health services and epidemiology research have tremendous potential to advance diabetes prevention and control, and the NIH Roadmap agenda of translation from bench to bedside to community. The MHSR Core will make cutting-edge expertise in these areas newly available to the DRTC research base, expanding the scientific armamentarium and capacity of diabetes researchers at UAB.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Comprehensive Center (P60)
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Special Emphasis Panel (ZDK1-GRB-S (O1))
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University of Alabama Birmingham
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Hunter, Gary R; Moellering, Douglas R; Carter, Stephen J et al. (2017) Potential Causes of Elevated REE after High-Intensity Exercise. Med Sci Sports Exerc 49:2414-2421
Willig, Amanda L; Kramer, Philip A; Chacko, Balu K et al. (2017) Monocyte bioenergetic function is associated with body composition in virologically suppressed HIV-infected women. Redox Biol 12:648-656
Hunter, Gary R; Plaisance, Eric P; Carter, Stephen J et al. (2017) Why intensity is not a bad word: Optimizing health status at any age. Clin Nutr :
Ingram, K H; Hunter, G R; James, J F et al. (2017) Central fat accretion and insulin sensitivity: differential relationships in parous and nulliparous women. Int J Obes (Lond) 41:1214-1217
Snyder, Peter J; Kopperdahl, David L; Stephens-Shields, Alisa J et al. (2017) Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial. JAMA Intern Med 177:471-479
Rowe, Glenn C; Asimaki, Angeliki; Graham, Evan L et al. (2017) Development of dilated cardiomyopathy and impaired calcium homeostasis with cardiac-specific deletion of ESRR?. Am J Physiol Heart Circ Physiol 312:H662-H671
Carter, Stephen J; Plaisance, Eric P; Fisher, Gordon et al. (2017) Alterations in Hemoglobin and Serum 25-hydroxyvitamin D are Related Before and After Weight Loss Independent of African Admixture. Int J Sport Nutr Exerc Metab 27:59-66
Budoff, Matthew J; Ellenberg, Susan S; Lewis, Cora E et al. (2017) Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone. JAMA 317:708-716
Prigge, Justin R; Coppo, Lucia; Martin, Sebastin S et al. (2017) Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase. Cell Rep 19:2771-2781
Resnick, Susan M; Matsumoto, Alvin M; Stephens-Shields, Alisa J et al. (2017) Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment. JAMA 317:717-727

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