The goal of this application is to establish the Contextual Health Disparities-Core (COHD) in the Northern Manhattan Center of Excellence in Minority Health and Health Disparities at Columbia University (NOCEMHD) in response to RFA-MD-11-008, """"""""Limited Competition: NIMHD Revision Applications to Support Environmental Health Disparities Research (P60)."""""""" The COHD will be established through a partnership with the Center for Study of Social Inequalities and Health (CSSIH) at the Mailman School of Public Health (MSPH), (director, Bruce Link, PhD). The leader of the COHD will be Dr. Link. The co-leader of this core will be Dr. Dana March. Research in NOCEMHD has focused on cohort studies and clinical trials examining determinants of minority health at the individual level, particularly in our focus areas of cardiovascular conditions (diabetes, hypertension), mental health (cognition, depression), and their coexistence. However, environmental factors interact with individual level factors to determine health outcomes in cardiovascular conditions and mental health. We refer to these factors as Health Disparity Environmental Factors (HDEF). We will collect a battery of validated measures of these HDEF used by the CSSIH in 4 ongoing NOCEMHD studies: The Northern Manhattan Study of Metabolism and Mental Health (NOMEM), The Northern Manhattan Community Outreach Project (NOCHOP), The Northern Manhattan Caregiver Intervention Project (NOCIP), and The Counseling Adults to Control Hypertension Study . (COACH). NOMEM is a cohort study. COACH, NOCHOP, and NOCIP are clinical trials.
Our specific aims (SA) are: SA 1: To examine in NOMEM cross-sectional analyses the respective contributions of HDEF at the national, state, city, neighborhood, and individual levels to proximal behavioral and biological risk and protective factors for diabetes and depression in a midlife Hispanic population;SA2: To examine how HDEF at the national, state, city, neighborhood, and individual levels modify the response to the community-based interventions in COACH, NOCHOP, and NOCIP. The rich data collected with support from this application will be part of our data and biospecimen repository (DBR) managed by the NOCEMHD Research Core.

Public Health Relevance

Funding of this application will support collection of data on health disparities environmental factors in Northern Manhattan. These data will allow us to understand environmental determinants of cardiovascular conditions in mental health in Northern Manhattan. Furthermore, these data will allow us to understand how environmental factors modify the effect of community based interventions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Comprehensive Center (P60)
Project #
3P60MD000206-09S1
Application #
8311964
Study Section
Special Emphasis Panel (ZMD1-RN (07))
Program Officer
Rajapakse, Nishadi
Project Start
2003-02-10
Project End
2013-01-31
Budget Start
2011-09-22
Budget End
2012-01-31
Support Year
9
Fiscal Year
2011
Total Cost
$572,320
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Reitz, Christiane; Guzman, Vanessa A; Narkhede, Atul et al. (2017) Relation of Dysglycemia to Structural Brain Changes in a Multiethnic Elderly Cohort. J Am Geriatr Soc 65:277-285
Cortés, Yamnia I; Arcia, Adriana; Kearney, Joan et al. (2017) Urban-Dwelling Community Members' Views on Biomedical Research Engagement. Qual Health Res 27:130-137
March, Dana; Williams, Jasmine; Wells, Shayla et al. (2015) Discrimination and Depression among Urban Hispanics with Poorly Controlled Diabetes. Ethn Dis 25:130-7
Lucero, Robert J; Kearney, Joan; Cortes, Yamnia et al. (2015) Benefits and Risks in Secondary Use of Digitized Clinical Data: Views of Community Members Living in a Predominantly Ethnic Minority Urban Neighborhood. AJOB Empir Bioeth 6:12-22
Luchsinger, José A; Cabral, Rafi; Eimicke, Joseph P et al. (2015) Glycemia, Diabetes Status, and Cognition in Hispanic Adults Aged 55-64 Years. Psychosom Med 77:653-63
Luchsinger, José A; Tipiani, Dante; Torres-Patiño, Gabriela et al. (2015) Characteristics and mental health of Hispanic dementia caregivers in New York City. Am J Alzheimers Dis Other Demen 30:584-90
Luchsinger, José A; Lehtisalo, Jenni; Lindström, Jaana et al. (2015) Cognition in the Finnish diabetes prevention study. Diabetes Res Clin Pract 108:e63-6
Cabassa, Leopoldo J; Stefancic, Ana; O'Hara, Kathleen et al. (2015) Peer-led healthy lifestyle program in supportive housing: study protocol for a randomized controlled trial. Trials 16:388
Palmas, Walter; Findley, Sally E; Teresi, Jeanne et al. (2015) Response to comment on Palmas et al. Results of the Northern Manhattan Diabetes Community Outreach Project: a randomized trial studying a community health worker intervention to improve diabetes care in Hispanic adults. Diabetes Care 2014;37:963-969. Diabetes Care 38:e59
Fitzpatrick, Annette L; Rapp, Stephen R; Luchsinger, José et al. (2015) Sociodemographic Correlates of Cognition in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Geriatr Psychiatry 23:684-97

Showing the most recent 10 out of 92 publications