This application proposes to renew the P60 Center of Excellence for Health Disparities Research: El Centro, at the University of Miami School of Nursing and Health Studies. In the four years since funded. El Centro has developed a well-funding infrastructure, built community and academic alliances, expanded our health disparities (HD) research training, and conducted innovative research studies to improve minority health and reduce HD. El Centro aims to reduce HD in a constellation of behaviorally-rooted health conditions that disproportionately affect minority groups: HIV/AIDS and other sexually transmitted infections, substance abuse, intimate partner violence, and associated mental and physical health conditions. El Centro pursues its mission through the following thematic approaches which Inform all activities, 1) development, evaluation and dissemination of culturally-tailored interventions;2) addressing culturally-related root causes and protective factors that impact multiple HD conditions;3) culturally-informed, community-engaged and technology assisted methodologies;4) nurturing the career development of emerging HD investigators, particularly those from HD populations and 5) interdisciplinary team science. This application proposes two new randomized translational trials ("SEPA III" and "SET-Recovery") and will have one randomized trial carried over from the current funding period ("CIFTA-Prevention"). We propose four Cores: 1) Administrative, 2) Research, 3) Research Training and Education, and 4) Community Engagement, Dissemination and Implementation, which is a new Core. El Centro has expanded its priority populations beyond Hispanics to include Blacks and sexual minority groups, and includes capacity-building initiatives with Latin America and the Caribbean. El Centro investigators are ethnically diverse and include nationally recognized senior investigators spanning the disciplines of anthropology, economics, education, epidemiology, health policy, medicine, nursing, nutrition, psychology and public health. The University of Miami Is ideally suited for an HD Center of Excellence due to its commitment to addressing HD, to training minority students and because of the ethnic diversity of South Florida and its proximity to Latin America and the Caribbean.

Public Health Relevance

HIV and other sexually transmitted infections, substance abuse, intimate partner violence and associated health problems are preventable conditions that disproportionately affect U.S. Hispanics, Blacks and sexual minority groups as well as people of Latin America and the Caribbean, whose wellbeing is inextricably tied to the wellbeing of people in the U.S. These inequitable differences increase the burden of disease for the affected groups, and are an issue of economic and social importance for all Americans.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Comprehensive Center (P60)
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Special Emphasis Panel (ZMD1-RN (02))
Program Officer
Castille, Dorothy M
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University of Miami Coral Gables
Schools of Nursing
Coral Gables
United States
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Villegas, Natalia; Santisteban, Daniel; Cianelli, Rosina et al. (2015) Pilot testing an internet-based STI and HIV prevention intervention with Chilean women. J Nurs Scholarsh 47:106-16
De Santis, Joseph P; Garcia, Ana; Chaparro, Aida et al. (2014) Integration versus disintegration: a grounded theory study of adolescent and young adult development in the context of perinatally-acquired HIV infection. J Pediatr Nurs 29:422-35
De Santis, Joseph P; Gonzalez-Guarda, Rosa; Provencio-Vasquez, Elias et al. (2014) The Tangled Branches (Las Ramas Enredadas): sexual risk, substance abuse, and intimate partner violence among Hispanic men who have sex with men. J Transcult Nurs 25:23-32
McCabe, Brian E; Feaster, Daniel J; Mitrani, Victoria B (2014) Health correlates of co-occurring substance use for women with HIV in cocaine use recovery. Addict Behav 39:725-8
Villegas, N; Santisteban, D; Cianelli, R et al. (2014) The development, feasibility and acceptability of an Internet-based STI-HIV prevention intervention for young Chilean women. Int Nurs Rev 61:55-63
De Santis, Joseph P; Valdes, Beatriz; Provencio-Vasquez, Elias et al. (2014) A Comparison of Substance Use Behaviors of Hispanic Men by Sexual Orientation. Nurs Health (Alhambra) 2:9-17
Cianelli, Rosina; Villegas, Natalia; Lawson, Sarah et al. (2013) Unique factors that place older Hispanic women at risk for HIV: intimate partner violence, machismo, and marianismo. J Assoc Nurses AIDS Care 24:341-54
Gonzalez-Guarda, R M; Cummings, A M; Becerra, M et al. (2013) Needs and preferences for the prevention of intimate partner violence among Hispanics: a community's perspective. J Prim Prev 34:221-35
McCabe, Brian E; Santisteban, Daniel A; Mena, Maite P et al. (2013) Engagement, retention, and abstinence for three types of opioid users in Florida. Subst Use Misuse 48:623-34
Vermeesch, Amber L; Gonzalez-Guarda, Rosa M; Hall, Rosemary et al. (2013) Predictors of depressive symptoms among Hispanic women in South Florida. West J Nurs Res 35:1325-38

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