Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Transition Award (R00)
Project #
3R00CA125892-04S1
Application #
7937487
Study Section
Special Emphasis Panel (ZCA1-RTRB-A (O1))
Program Officer
Snyderwine, Elizabeth G
Project Start
2009-09-30
Project End
2011-09-29
Budget Start
2009-09-30
Budget End
2011-09-29
Support Year
4
Fiscal Year
2009
Total Cost
$166,000
Indirect Cost
Name
City of Hope/Beckman Research Institute
Department
Type
DUNS #
027176833
City
Duarte
State
CA
Country
United States
Zip Code
91010
Tsuyada, Akihiro; Wang, Shizhen Emily (2013) Fibroblast-derived CCL2 induces cancer stem cells--response. Cancer Res 73:1032-3
Wang, Shizhen Emily; Lin, Ren-Jang (2013) MicroRNA and HER2-overexpressing cancer. Microrna 2:137-47
Tsuyada, Akihiro; Chow, Amy; Wu, Jun et al. (2012) CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res 72:2768-79
Chandra, Manasa; Zang, Shengbing; Li, Haiqing et al. (2012) Nuclear translocation of type I transforming growth factor ýý receptor confers a novel function in RNA processing. Mol Cell Biol 32:2183-95
Wang, Shizhen Emily (2011) The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-? Signaling in Breast Cancer Malignancy. J Signal Transduct 2011:804236
Wang, Y; Yu, Y; Tsuyada, A et al. (2011) Transforming growth factor-? regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene 30:1470-80
Chow, Amy; Arteaga, Carlos L; Wang, Shizhen Emily (2011) When tumor suppressor TGF? meets the HER2 (ERBB2) oncogene. J Mammary Gland Biol Neoplasia 16:81-8
Yu, Yang; Wang, Yujun; Ren, Xiubao et al. (2010) Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor ? contributes to chemoresistance in breast cancer cells. Mol Cancer Res 8:1633-42
Wang, S E; Yu, Y; Criswell, T L et al. (2010) Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators. Oncogene 29:3335-48
Wang, Shizhen Emily; Hinow, Peter; Bryce, Nicole et al. (2009) A mathematical model quantifies proliferation and motility effects of TGF-? on cancer cells. Comput Math Methods Med 10:71-83

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