Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA008025-03
Application #
3111930
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1989-01-01
Project End
1991-12-31
Budget Start
1991-01-01
Budget End
1991-12-31
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Li, X Y; McArdle, J J (1997) Novel transient outward K+ current of mature murine hippocampal neurones. Pflugers Arch 434:195-202
Ye, J H; McArdle, J J (1996) 2,3-Butanedione monoxime modifies the glycine-gated chloride current of acutely isolated murine hypothalamic neurons. Brain Res 735:20-9
Ye, J H; McArdle, J J (1995) Excitatory amino acid induced currents of isolated murine hypothalamic neurons and their suppression by 2,3-butanedione monoxime. Neuropharmacology 34:1259-72
Xiao, Y F; McArdle, J J (1995) Effects of 2,3-butanedione monoxime on blood pressure, myocardial Ca2+ currents, and action potentials of rats. Am J Hypertens 8:1232-40
Brightman, T; Ye, J H; Ortiz-Jimenez, E et al. (1995) 2,3-Butanedione monoxime protects mice against the convulsant effect of picrotoxin by facilitating GABA-activated currents. Brain Res 678:110-6
Xiao, Y F; McArdle, J J (1995) Activation of protein kinase A partially reverses the effects of 2,3-butanedione monoxime on the transient outward K+ current of rat ventricular myocytes. Life Sci 57:335-43
Huang, G J; McArdle, J J (1994) Role of the GTP-binding protein G(o) in the suppressant effect of ethanol on voltage-activated calcium channels of murine sensory neurons. Alcohol Clin Exp Res 18:608-15
Xiao, Y F; McArdle, J J (1994) Elevated density and altered pharmacologic properties of myocardial calcium current of the spontaneously hypertensive rat. J Hypertens 12:783-90
Sellin, L C; McArdle, J J (1994) Multiple effects of 2,3-butanedione monoxime. Pharmacol Toxicol 74:305-13
Huang, G J; McArdle, J J (1993) Chronic ingestion of ethanol increases the number of Ca2+ channels of hippocampal neurons of long-sleep but not short-sleep mice. Brain Res 615:328-30

Showing the most recent 10 out of 17 publications