EXCEED THESPACE PROVIDED. There is considerable evidence that treatmentfor alcohol disorders can lead to significant improvements in substance use and psychosocial problem severity. However, a significantpercentage of patients relapse to heavy drinking after primary treatment has ended. Patients are therefore frequently referred to continuingcare, or 'aftercare,' programsin an effort to prevent relapse anddecrease theprobability of additional rehabilitation treatments. However, current models of continuing care may not be adequate for the long-term management of a chronic, relapsing disorder such as alcoholism. One possible approach for improving the long-term management of alcoholism is low intensity monitoring and counseling, with the provision to increase the intensity of treatmentwhen warranted. Alcohol dependent patients who have completed 3 weeks of intensive outpatient treatmentwill be randomly assigned to one of the following interventions: (1) continued participation in standard outpatient treatment withoutadditional intervention (treatment as usual, or TAU); (2)TAU plus brief monitoring and feedback via telephone on a tapered schedule out to 18months (IMF); or (3) TAU plus brief monitoring and counseling via telephone on a tapered schedule out to 18months (TMC). The TMC condition will also include an 'adaptive' component, in whichintensity of treatment can be increased when specified criteria have been met The inclusion of the IMF condition will makeit possible to determine whether simple monitoring with minimal feedback, withoutthe addition of counseling and adaptive provisions, is sufficient to maintain good outcomes. Patients will be followed up at 4,8,12,18, and24 months post intake into the study. Follow-up assessments will include measures of drinking and drug use (e.g., self-report, collateral reports, urine, and blood), treatment process and potential mediating factors (e.g., motivation, therapeutic alliance, self-efficacy, mood, social support, self-help involvement), psychosocial problem severity, and utilizationof health and social services. TMF and TMC are predicted to produce better alcohol use outcomes thanTAU. A group by time interaction is also jredicted, in which an effect favoring TMC over TMF will emerge over time. Standard and innovativeanalyses will be done to examine the potential mediating effects of treatmentprocess variables and other factors. Secondary analyses will seek to identify variables that predict which patients benefit to the greatest degree from long-term monitoring. Economic analyses will determine the cost-effectiveness and benefit-cost of TMC and TMF relative to TAU, andto ach other. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA014850-03
Application #
6945949
Study Section
Special Emphasis Panel (ZAA1-AA (04))
Program Officer
Lowman, Cherry
Project Start
2003-09-19
Project End
2008-08-31
Budget Start
2005-09-01
Budget End
2006-08-31
Support Year
3
Fiscal Year
2005
Total Cost
$572,363
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Van Horn, Deborah H A; Rennert, Lior; Lynch, Kevin G et al. (2014) Social network correlates of participation in telephone continuing care for alcohol dependence. Am J Addict 23:447-52
McKay, James R; Van Horn, Deborah; Rennert, Lior et al. (2013) Factors in sustained recovery from cocaine dependence. J Subst Abuse Treat 45:163-72
McKay, James R; Van Horn, Deborah; Oslin, David W et al. (2011) Extended telephone-based continuing care for alcohol dependence: 24-month outcomes and subgroup analyses. Addiction 106:1760-9
McKay, James R; Hiller-Sturmhofel, Susanne (2011) Treating alcoholism as a chronic disease: approaches to long-term continuing care. Alcohol Res Health 33:356-70
Lynch, Kevin G; Van Horn, Deborah; Drapkin, Michelle et al. (2010) Moderators of response to telephone continuing care for alcoholism. Am J Health Behav 34:788-800
McKay, James R; Van Horn, Deborah H A; Oslin, David W et al. (2010) A randomized trial of extended telephone-based continuing care for alcohol dependence: within-treatment substance use outcomes. J Consult Clin Psychol 78:912-23
McKay, James R (2009) Continuing care research: what we have learned and where we are going. J Subst Abuse Treat 36:131-45
McKay, James R (2007) Lessons learned from psychotherapy research. Alcohol Clin Exp Res 31:48s-54s
Morgenstern, Jon; McKay, James R (2007) Rethinking the paradigms that inform behavioral treatment research for substance use disorders. Addiction 102:1377-89
Murphy, Susan A; Lynch, Kevin G; Oslin, David et al. (2007) Developing adaptive treatment strategies in substance abuse research. Drug Alcohol Depend 88 Suppl 2:S24-30

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