This proposal extends a line of international collaborative research for preventing Fetal Alcohol Syndrome (FAS) and Alcohol Related Neurodevelopmental Disorder (ARND) in Russia. Russia is a country with very high rates of alcohol use (WHO, 1999), including among women in their childbearing years. FAS/ARND are completely preventable by avoiding alcohol use during pregnancy. Our prior studies have suggested that although many Russian women reduce alcohol consumption after pregnancy is diagnosed, few recognize the risks involved in combining alcohol use with the potential to become pregnant, prior to the diagnosis of pregnancy, and therefore may be at risk for substantial fetal alcohol exposure during the early weeks of pregnancy. Therefore, a preconception dual-focus (alcohol use/pregnancy risk) approach targeting at-risk women is indicated for primary prevention of alcohol exposed pregnancies (AEP). The overarching aim of the study is to reduce risk for AEP in Russia. The proposed study is a two-arm, 20- site, site-randomized trial testing a Brief Physician Intervention (BPI) for at-risk women (at-risk drinking childbearing age women who are heterosexually active, and not consistently using contraception). The trial will determine whether physicians, trained in a dual-focused brief motivational intervention and monitored for performance, can foster greater reduction of women's risk behaviors compared to standard care. If effective, the BPI primary prevention protocol could be disseminated throughout the existing Russian health care system and public women's clinics. The project builds on two current research projects funded by the NIH and CDC and an established collaboration between scientists from medicine, psychology, and public health in the US and Russia. The project will be conducted through a consortium between the University of Oklahoma Health Sciences Center, St. Petersburg State University, and the Nizhniy Novgorod Institute for Applied Psychology/Nizhniy Novgorod State Pedagogical University in Russia. The first phase of the collaboration involved capacity building and obtaining data critical to developing FAS/ARND prevention Russia. The second phase involved developing professional training and public print materials for primary prevention. In our prior studies, Russian women identified OBG physicians as a major influence on their health behaviors, supporting the selection of BPI as the primary prevention intervention for this proposal. The project is designed to increase the sustainable capacity of Russian researchers to pursue FAS/ARND prevention research and to strengthen our existing international multidisciplinary collaboration. The proposed study would be the first randomized trial targeted at alcohol exposed pregnancies and preventing FAS/ARND in Russia.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
3R01AA016234-05S1
Application #
8532076
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (50))
Program Officer
Scott, Marcia S
Project Start
2007-09-20
Project End
2013-08-31
Budget Start
2012-09-15
Budget End
2013-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$88,800
Indirect Cost
$28,800
Name
University of Oklahoma Health Sciences Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
878648294
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
Balachova, Tatiana; Shaboltas, Alla; Nasledov, Andrey et al. (2016) Alcohol and HIV Risk Among Russian Women of Childbearing Age. AIDS Behav :
Balachova, Tatiana; Bard, David; Bonner, Barbara et al. (2016) Do attitudes and knowledge predict at-risk drinking among Russian women? Am J Drug Alcohol Abuse 42:306-15
Balachova, Tatiana N; Batluk, Julia V; Bryant, Kendall J et al. (2015) International collaboration in HIV prevention research: evidence from a research seminar in Russia. AIDS Res Hum Retroviruses 31:163-72
Balachova, Tatiana; Sobell, Linda Carter; Agrawal, Sangeeta et al. (2015) Using a single binge drinking question to identify Russian women at risk for an alcohol-exposed pregnancy. Addict Behav 46:53-7
Bax, Ami C; Geurts, Carrie D; Balachova, Tatiana N (2015) Improving Recognition of Children Affected by Prenatal Alcohol Exposure: Detection of Exposure in Pediatric Care. Curr Dev Disord Rep 2:165-174
Balachova, Tatiana; Bonner, Barbara L; Chaffin, Mark et al. (2013) Brief FASD prevention intervention: physicians' skills demonstrated in a clinical trial in Russia. Addict Sci Clin Pract 8:1
Balachova, Tatiana; Bonner, Barbara; Chaffin, Mark et al. (2012) Women's alcohol consumption and risk for alcohol-exposed pregnancies in Russia. Addiction 107:109-17
Balachova, Tatiana N; Bonner, Barbara L; Isurina, Galina L et al. (2007) Use of focus groups in developing FAS/FASD prevention in Russia. Subst Use Misuse 42:881-94