The proposed study would examine issues related to the course, including persistence and desistance, of alcohol use and AUDs in early midadulthood for men. Such behaviors are costly to society both financially and in personal and family distress. These issues would be examined by utilizing an existing longitudinal data set currently spanning later childhood to ages 31-32 years, including 23 yearly assessments of alcohol use, and adding two new waves of data collection at ages 35-36 and 37-38 years. Combining these two new waves with existing data from ages 29-30, 30-31, and 31-32 will provide a total of 5 waves in the early midadult period. The multimethod/multiagent study of a community sample at risk for conduct problem and other risk behaviors began with two cohorts of fourth-grade boys (total N = 206);the retention rate at the last wave was 95% of living subjects (N = 191, ages 31-32 years). The study focused on contextual, family of origin, and peer risk factors based on a social learning model, and data are available on romantic partners. We plan to use a Dynamic Developmental Systems approach, based on aspects of past and current social- contextual influences, to study heterogeneity in the course of alcohol use and AUDs and predictors of the course, including general and specific risk factors within the realms of family, peer, psychopathology, and early to midadult risk and social influences, including romantic partner behaviors. Early onset of alcohol use was assessed prospectively by age at first drink and age at first drunken experience. Association of growth and heterogeneity in growth of alcohol use will be examined also in relation to heterogeneity in the course of co- morbid substance use (tobacco, marijuana, other illicit drugs, non-prescription and over-the-counter drugs), and gambling behavior. In addition, prediction models of treatment seeking will be examined. The two new assessments will include self-report, peer report, and records data (police and DMV records). Reports from intimate partners are available in a companion study. A variety of complementary developmental modeling and prediction techniques will be used to capture the degree to which prior family and contextual factors, and prior behaviors in childhood and adolescence (e.g., antisocial behavior in childhood) and similar contextual, social relationships, and behavioral factors in adulthood, can explain changes in the course of behaviors across the early adult period.

Public Health Relevance

Alcohol use in early mid-adulthood is extremely costly at the personal, family, community, and national levels, and is associated with early mortality. Alcohol abuse/dependence is the most common of all DSM disorders for men. Almost one in four victims of violent crime report that the offender had been drinking prior to the crime. The economic costs of alcohol abuse and dependence were estimated at close to $200 billion in the U.S. in 1998. Focus areas of Healthy People 2010 (U.S. DHHS) include prevention and control of the use of tobacco and substance abuse. The proposed study will shed new light on the persistence and desistance of use of alcohol and other substances in early midadulthood for men from at-risk backgrounds.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA018669-04
Application #
8299175
Study Section
Risk, Prevention and Intervention for Addictions Study Section (RPIA)
Program Officer
Godette, Dionne
Project Start
2009-09-30
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
4
Fiscal Year
2012
Total Cost
$648,983
Indirect Cost
$210,481
Name
Oregon Social Learning Center, Inc.
Department
Type
DUNS #
084418656
City
Eugene
State
OR
Country
United States
Zip Code
97401
Capaldi, Deborah M; Kerr, David C R; Eddy, J Mark et al. (2016) Understanding Persistence and Desistance in Crime and Risk Behaviors in Adulthood: Implications for Theory and Prevention. Prev Sci 17:785-93
Tiberio, Stacey S; Capaldi, Deborah M; Kerr, David C R et al. (2016) Parenting and the development of effortful control from early childhood to early adolescence: A transactional developmental model. Dev Psychopathol 28:837-53
Capaldi, Deborah M; Tiberio, Stacey S; Kerr, David C R et al. (2016) The Relationships of Parental Alcohol Versus Tobacco and Marijuana Use With Early Adolescent Onset of Alcohol Use. J Stud Alcohol Drugs 77:95-103
Capaldi, Deborah M; Tiberio, Stacey S; Washburn, Isaac J et al. (2015) Growth, Persistence, and Desistance of Alcohol Use for At-Risk Men in Their 30s. Alcohol Clin Exp Res 39:1203-11
Washburn, Isaac J; Capaldi, Deborah M (2015) Heterogeneity in men's marijuana use in the 20s: adolescent antecedents and consequences in the 30s. Dev Psychopathol 27:279-91
Feingold, Alan; Capaldi, Deborah M; Owen, Lee D (2015) Proximal vs. distal predictors of alcohol use disorders and treatment utilization in at-risk men in early middle age. Compr Psychiatry 61:64-71
Kerr, David C R; Tiberio, Stacey S; Capaldi, Deborah M (2015) Contextual risks linking parents' adolescent marijuana use to offspring onset. Drug Alcohol Depend 154:222-8
Feingold, Alan; Washburn, Isaac J; Tiberio, Stacey S et al. (2015) Changes in the Associations of Heavy Drinking and Drug Use with Intimate Partner Violence in Early Adulthood. J Fam Violence 30:27-34
Kim, Hyoun K; Tiberio, Stacey S; Capaldi, Deborah M et al. (2015) Intimate partner violence and diurnal cortisol patterns in couples. Psychoneuroendocrinology 51:35-46
Feingold, Alan (2015) Confidence interval estimation for standardized effect sizes in multilevel and latent growth modeling. J Consult Clin Psychol 83:157-68

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