The proportion of individuals in the United States who are living into old age had risen dramatically in the past several decades and is expected to continue its upward climb. With this has come a growing interest in identifying ways to help aging adults maintain their health, functional independence, and overall quality of life. The primary goal of this proposal is to evaluate a randomized controlled clinical trial of an intervention designed to improve emotional well-being, increase health behaviors, and enhance problem-solving skills. This intervention will provide skills training in two determinants of successful aging: problem solving and physical exercise. Two hundred forty-eight community-residing adults over age 75 will be randomly assigned to one of four treatment conditions in a two-by-two factorial design: Problem-solving (PS) only, Exercise (EX) only, PS+EX, and Usual Care Control (UCC). Subjects will be recruited from a cohort of older adults who are members of a community-based HMO on whom extensive data are already available. Primary outcome measures include the Geriatric Depression Scale (for assessing depression and emotional well-being), the SF-36 (for assessing health and function), and the Everyday Problem-Solving Test (for assessing problem-solving skills). Secondary outcome measures will assess depression and emotional well-being, physical health, cost of care, and mortality. Outcome measures will be collected at the time of enrollment into the study (baseline), at 3 months (post-treatment), and four times over the course of the 2-year follow-up. It is hypothesized that the PS and EX conditions will be effective in improving emotional well-being and physical health. PS will be effective in improving problem-solving; and the combination of PS+EX will be more effective than the individual interventions in improving all areas. It is also hypothesized that these effects will be maintained over 2 years, and that subjects in PS, EX, and PS+EX will improve on measures of disability and independence, health utilization and cost.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG014777-04
Application #
6650190
Study Section
Special Emphasis Panel (ZRG1-RPHB-3 (01))
Program Officer
Elias, Jeffrey W
Project Start
2000-09-30
Project End
2005-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
4
Fiscal Year
2003
Total Cost
$792,389
Indirect Cost
Name
University of Washington
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
McGough, Ellen L; Kelly, Valerie E; Weaver, Kurt E et al. (2018) Limbic and Basal Ganglia Neuroanatomical Correlates of Gait and Executive Function: Older Adults With Mild Cognitive Impairment and Intact Cognition. Am J Phys Med Rehabil 97:229-235
Weaver, Kurt E; Richards, Todd L; Logsdon, Rebecca G et al. (2015) Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment. Biomed Res Int 2015:610605
McGough, E L; Cochrane, B B; Pike, K C et al. (2013) Dimensions of physical frailty and cognitive function in older adults with amnestic mild cognitive impairment. Ann Phys Rehabil Med 56:329-41
McGough, Ellen L; Kelly, Valerie E; Logsdon, Rebecca G et al. (2011) Associations between physical performance and executive function in older adults with mild cognitive impairment: gait speed and the timed ""up & go"" test. Phys Ther 91:1198-207
Teri, Linda; McCurry, Susan M; Logsdon, Rebecca G et al. (2011) A randomized controlled clinical trial of the Seattle Protocol for Activity in older adults. J Am Geriatr Soc 59:1188-96
Logsdon, Rebecca G; McCurry, Susan M; Pike, Kenneth C et al. (2009) Making physical activity accessible to older adults with memory loss: a feasibility study. Gerontologist 49 Suppl 1:S94-9
Teri, L; Logsdon, R G; McCurry, S M (2008) Exercise interventions for dementia and cognitive impairment: the Seattle Protocols. J Nutr Health Aging 12:391-4
Logsdon, Rebecca G; McCurry, Susan M; Teri, Linda (2007) Evidence-Based Interventions to Improve Quality of Life for Individuals with Dementia. Alzheimers care today 8:309-318
McCurry, Susan M; Logsdon, Rebecca G; Teri, Linda et al. (2007) Evidence-based psychological treatments for insomnia in older adults. Psychol Aging 22:18-27
Logsdon, Rebecca G; McCurry, Susan M; Teri, Linda (2005) A home health care approach to exercise for persons with Alzheimer's disease. Care Manag J 6:90-7

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