The research described in this competing renewal proposal seeks through five aims to maintain and enhance the Americans'Changing Lives (ACL) study, which was started in 1986, and is the oldest on-going nationally- representative prospective study of a broad range of socioeconomic and psychosocial determinants of health, and of how health and health disparities play out over the full life course. It is a unique research project and major public use data set for analyzing and understanding social disparities in the way health changes with age, especially the postponement or compression of mortality, morbidity, functional limitations, and disability over the entire adult life course. The ACL study focuses on and contributes to the two overarching goals of the U.S. Public Health Service's Healthy People 2010 strategic plan: 1) increasing healthy active life expectancy and 2) reducing social disparities in health. The five specific aims of this proposal are: 1) to extend the longitudinal follow-up of surviving members of the 1986 ACL sample by conducting a fifth wave of data collection and continuing annual mortality ascertainment using the National Death Index, death certificate verification, and other mortality tracking processes through at least 2013;2) to develop a methodological/biostatistical core for ACL which will a) provide expertise to the project for increasingly complex analyses of the determinants of long term changes and trajectories in health, and b) develop and apply innovative statistical/methodological research to improve longitudinal analysis and adjust for selection and attrition in analyses, thus, improving our and others'ability to utilize ACL and similar longitudinal data;3) to understand mechanisms underlying social disparities in morbidity and mortality and the compression thereof;4) to add new measures regarding medical care, disability and impairment to ACL Wave 5 so as to expand the health status outcomes under study and investigate the role of selected biomedical interventions in maintaining, enhancing or alleviating social disparities in the way different health outcomes change with age;and 5) to capitalize on existing measures of work conditions and transitions and add new ones to ACL5 in order to investigate changing patterns and sequencing of paid work, unpaid productive activities, and """"""""retirement"""""""", in the context of current crises of the American and world economies.

Public Health Relevance

This project extends the Americans'Changing Lives (ACL) - a national longitudinal study of social determinants of and disparities in health and the way health changes with age. The proposed project would re-interview survivors a fifth time and extend mortality follow-up through at least 2013. The study focuses on and contributes to the two overarching goals of the U.S. Public Health Service: increasing healthy active life expectancy and reducing social disparities in health.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG018418-10
Application #
8467656
Study Section
Special Emphasis Panel (ZRG1-PSE-B (04))
Program Officer
Patmios, Georgeanne E
Project Start
2000-08-01
Project End
2016-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
10
Fiscal Year
2013
Total Cost
$359,804
Indirect Cost
$128,419
Name
University of Michigan Ann Arbor
Department
Biostatistics & Other Math Sci
Type
Organized Research Units
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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Assari, Shervin; Lankarani, Maryam Moghani; Burgard, Sarah (2016) Black-white difference in long-term predictive power of self-rated health on all-cause mortality in United States. Ann Epidemiol 26:106-14
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Assari, Shervin; Burgard, Sarah; Zivin, Kara (2015) Long-Term Reciprocal Associations Between Depressive Symptoms and Number of Chronic Medical Conditions: Longitudinal Support for Black-White Health Paradox. J Racial Ethn Health Disparities 2:589-97
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