Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG024011-02
Application #
6801068
Study Section
Special Emphasis Panel (ZAG1-ZIJ-9 (J2))
Program Officer
Snyder, Stephen D
Project Start
2003-09-16
Project End
2008-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
2
Fiscal Year
2004
Total Cost
$324,904
Indirect Cost

  Institution

Name
University of Washington
Department
Pathology
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Latimer, Caitlin S; Flanagan, Margaret E; Cimino, Patrick J et al. (2017) Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son. J Huntingtons Dis 6:337-348
Yang, Yue; Shiao, Christine; Hemingway, Jake Frederick et al. (2013) Suppressed retinal degeneration in aged wild type and APPswe/PS1ýýE9 mice by bone marrow transplantation. PLoS One 8:e64246
Shi, Ju; Wang, Qian; Johansson, Jenny U et al. (2012) Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease. Ann Neurol 72:788-98
Shi, Ju; Johansson, Jenny; Woodling, Nathaniel S et al. (2010) The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity. J Immunol 184:7207-18
Keene, C Dirk; Chang, Rubens C; Lopez-Yglesias, Americo H et al. (2010) Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrow. Am J Pathol 177:346-54
Montine, Thomas J; Sonnen, Joshua A; Milne, Ginger et al. (2010) Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT. PLoS One 5:e9340
Keene, C Dirk; Chang, Rubens; Stephen, Christina et al. (2009) Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2. Am J Pathol 174:2300-9
Cimino, Patrick J; Sokal, Izabela; Leverenz, James et al. (2009) DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer's disease brain. Am J Pathol 175:1622-30
Liang, Xibin; Wang, Qian; Shi, Ju et al. (2008) The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis. Ann Neurol 64:304-14
Sonnen, Joshua A; Montine, Kathleen S; Quinn, Joseph F et al. (2008) Biomarkers for cognitive impairment and dementia in elderly people. Lancet Neurol 7:704-14

Showing the most recent 10 out of 31 publications