The proposed project is based on an expanded biopsycho-ecological model of illness and disability which imports concepts from gerontology (frailty), psychiatry (failure to thrive and the biopsychosocial model), rehabilitation (health environmental integration), and sociology (the social model of disability). Understanding how health conditions limit the performance of activities and the patterns and severity of the activity limitations produced is essential in developing strategies to optimize function, independent living, and quality-of-life. We propose an """"""""Impairment Activity Staging System"""""""" for people 70 years of age and older living in the community who are experiencing limitations in the Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADLs). Our overall hypothesis is that both the mental and physical health conditions people view as limiting their abilities to perform activities and the particular ADL and IADL dysfunctions they experience will independently contribute to the prediction of 2- and 4-year functional recovery or decline, long term care (LTC) placement, and mortality.
The specific aims are to: 1. Develop and test the validity of the hierarchical 5-level staging systems of ADL and IADL functioning. Higher and lower stages will be derived separately for the ADL and IADLs according to the most common and expected patterns of functional decline and recovery. 2. Derive and test the validity of a 4-dimensional impairment classification scheme that groups the mental and physical health conditions people list as most responsible for causing their ADL or IADL limitations. Assignment to each dimension will be based on knowledge about pathology according to organ involvement (brain, neuro-musculoskeletal, cardiopulmonary, etc.), potential for severity, typical progression, and likelihood of mortality. 3. Test the independent contributions of the impairment and activity staging components of the full """"""""Impairment Activity Staging System"""""""" to predict 2- and 4-year functional recovery or decline, LTC placement, and mortality. The full classification will be assumed valid if each component shows cross sectional and predictive associations with concepts hypothesized to be clinically logically related to it, and if the health conditions and functional activity elements together prove to be more prognostic than either element alone.

Public Health Relevance

A 2007 Institute of Medicine (IOM) report called for the creation of a comprehensive disability monitoring system applying international classification functioning, disability and health (ICF) terminology and concepts. This proposal has relevance to public health because it will help us understand the life implications of Activities of daily living (ADL) and Instrumental activities of daily living (IADL) limitation, the determinants of dynamic changes in status, and recognize both severity (the magnitude of dysfunction summarized across multiple activities) and the type of limitation (the particular pattern of deficit across the activities). The system will be designed to assess the status, needs, and prognosis of individual people and in addition, project the changing patterns of need in the larger population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG032420-02
Application #
7916388
Study Section
Nursing Science: Adults and Older Adults Study Section (NSAA)
Program Officer
Patmios, Georgeanne E
Project Start
2009-08-15
Project End
2012-07-31
Budget Start
2010-08-01
Budget End
2012-07-31
Support Year
2
Fiscal Year
2010
Total Cost
$342,041
Indirect Cost
Name
University of Pennsylvania
Department
Biostatistics & Other Math Sci
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Schüssler-Fiorenza Rose, Sophia Miryam; Stineman, Margaret G; Pan, Qiang et al. (2017) Potentially Avoidable Hospitalizations among People at Different Activity of Daily Living Limitation Stages. Health Serv Res 52:132-155
Schüssler-Fiorenza Rose, Sophia Miryam; Xie, Dawei; Streim, Joel E et al. (2016) Identifying neuropsychiatric disorders in the Medicare Current Beneficiary Survey: the benefits of combining health survey and claims data. BMC Health Serv Res 16:537
Stineman, Margaret G; Xie, Dawei; Pan, Qiang et al. (2016) Understanding non-performance reports for instrumental activity of daily living items in population analyses: a cross sectional study. BMC Geriatr 16:64
Stineman, Margaret G; Streim, Joel E; Pan, Qiang et al. (2014) Activity Limitation Stages empirically derived for Activities of Daily Living (ADL) and Instrumental ADL in the U.S. Adult community-dwelling Medicare population. PM R 6:976-87; quiz 987
Brown, Janice; Kurichi, Jibby E; Xie, Dawei et al. (2014) Instrumental activities of daily living staging as a possible clinical tool for falls risk assessment in physical medicine and rehabilitation. PM R 6:316-23; quiz 323
Stineman, Margaret G; Zhang, Guangyu; Kurichi, Jibby E et al. (2013) Prognosis for functional deterioration and functional improvement in late life among community-dwelling persons. PM R 5:360-71
Schüssler-Fiorenza, C Miryam; Xie, Dawei; Pan, Qiang et al. (2013) Comparison of complex versus simple activity of daily living staging: validation of simple stages. Arch Phys Med Rehabil 94:1320-7
Henry-Sánchez, John T; Kurichi, Jibby E; Xie, Dawei et al. (2012) Do elderly people at more severe activity of daily living limitation stages fall more? Am J Phys Med Rehabil 91:601-10
Stineman, Margaret G; Henry-Sánchez, John T; Kurichi, Jibby E et al. (2012) Staging activity limitation and participation restriction in elderly community-dwelling persons according to difficulties in self-care and domestic life functioning. Am J Phys Med Rehabil 91:126-40
Stineman, Margaret G; Xie, Dawei; Pan, Qiang et al. (2012) All-cause 1-, 5-, and 10-year mortality in elderly people according to activities of daily living stage. J Am Geriatr Soc 60:485-92

Showing the most recent 10 out of 15 publications