Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI012710-20
Application #
2059915
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1975-06-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Weidanz, W P; Lafleur, G; Kita-Yarbro, A et al. (2011) Signalling through the IL-2 receptor ?(c) peptide (CD132) is essential for the expression of immunity to Plasmodium chabaudi adami blood-stage malaria. Parasite Immunol 33:512-6
Weidanz, William P; LaFleur, GayeLyn; Brown, Andrew et al. (2010) Gammadelta T cells but not NK cells are essential for cell-mediated immunity against Plasmodium chabaudi malaria. Infect Immun 78:4331-40
Lynch, Michelle M; Cernetich-Ott, Amy; Weidanz, William P et al. (2009) Prediction of merozoite surface protein 1 and apical membrane antigen 1 vaccine efficacies against Plasmodium chabaudi malaria based on prechallenge antibody responses. Clin Vaccine Immunol 16:293-302
van der Heyde, Henri C; Burns, James M; Weidanz, William P et al. (2007) Analysis of antigen-specific antibodies and their isotypes in experimental malaria. Cytometry A 71:242-50
van der Heyde, Henri C; Batchelder, Joan M; Sandor, Matyas et al. (2006) Splenic gammadelta T cells regulated by CD4+ T cells are required to control chronic Plasmodium chabaudi malaria in the B-cell-deficient mouse. Infect Immun 74:2717-25
Weidanz, William P; Batchelder, Joan M; Flaherty, P et al. (2005) Plasmodium chabaudi adami: use of the B-cell-deficient mouse to define possible mechanisms modulating parasitemia of chronic malaria. Exp Parasitol 111:97-104
Rummel, Thomas; Batchelder, Joan; Flaherty, Patrick et al. (2004) CD28 costimulation is required for the expression of T-cell-dependent cell-mediated immunity against blood-stage Plasmodium chabaudi malaria parasites. Infect Immun 72:5768-74
Gillman, Brad M; Batchelder, Joan; Flaherty, Patrick et al. (2004) Suppression of Plasmodium chabaudi parasitemia is independent of the action of reactive oxygen intermediates and/or nitric oxide. Infect Immun 72:6359-66
Cigel, Francine; Batchelder, Joan; Burns Jr, James M et al. (2003) Immunity to blood-stage murine malarial parasites is MHC class II dependent. Immunol Lett 89:243-9
Batchelder, Joan M; Burns Jr, James M; Cigel, Francine K et al. (2003) Plasmodium chabaudi adami: interferon-gamma but not IL-2 is essential for the expression of cell-mediated immunity against blood-stage parasites in mice. Exp Parasitol 105:159-66

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