Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI019335-24
Application #
6760128
Study Section
Immunobiology Study Section (IMB)
Program Officer
Chiodetti, Lynda
Project Start
1990-06-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
24
Fiscal Year
2004
Total Cost
$336,449
Indirect Cost
Name
University of Washington
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Bergsbaken, Tessa; Bevan, Michael J (2015) Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8? T cells responding to infection. Nat Immunol 16:406-14
Bergsbaken, Tessa; Bevan, Michael J (2015) Cutting Edge: Caspase-11 Limits the Response of CD8+ T Cells to Low-Abundance and Low-Affinity Antigens. J Immunol 195:41-5
Mehlhop-Williams, Erin R; Bevan, Michael J (2014) Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation. J Exp Med 211:345-56
Park, Heon; Tsang, Mark; Iritani, Brian M et al. (2014) Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development. Proc Natl Acad Sci U S A 111:7066-71
Zhang, Nu; Bevan, Michael J (2013) Transforming growth factor-? signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention. Immunity 39:687-96
Chu, Talyn; Tyznik, Aaron J; Roepke, Sarah et al. (2013) Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner. Cell Rep 3:701-8
Zhang, Nu; Bevan, Michael J (2012) TGF-? signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat Immunol 13:667-73
Prlic, Martin; Sacks, Jilian A; Bevan, Michael J (2012) Dissociating markers of senescence and protective ability in memory T cells. PLoS One 7:e32576
Zhang, Nu; Bevan, Michael J (2011) CD8(+) T cells: foot soldiers of the immune system. Immunity 35:161-8
Bevan, Michael J (2011) Understand memory, design better vaccines. Nat Immunol 12:463-5

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