Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI020506-09A5
Application #
2003284
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1984-07-01
Project End
1999-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Pediatrics
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Abramson, J S; Hudnor, H R (1995) Role of the sialophorin (CD43) receptor in mediating influenza A virus-induced polymorphonuclear leukocyte dysfunction. Blood 85:1615-9
Abramson, J S; Hudnor, H R (1994) Effect of priming polymorphonuclear leukocytes with cytokines (granulocyte-macrophage colony-stimulating factor [GM-CSF] and G-CSF) on the host resistance to Streptococcus pneumoniae in chinchillas infected with influenza A virus. Blood 83:1929-34
Abramson, J S; Wagner, M P; Ralston, E P et al. (1991) The ability of polymorphonuclear leukocyte priming agents to overcome influenza A virus-induced cell dysfunction. J Leukoc Biol 50:160-6
Wheeler, J G; Winkler, L S; Seeds, M et al. (1990) Influenza A virus alters structural and biochemical functions of the neutrophil cytoskeleton. J Leukoc Biol 47:332-43
Cassidy, L F; Lyles, D S; Abramson, J S (1989) Depression of polymorphonuclear leukocyte functions by purified influenza virus hemagglutinin and sialic acid-binding lectins. J Immunol 142:4401-6
Cassidy, L F; Lyles, D S; Abramson, J S (1988) Synthesis of viral proteins in polymorphonuclear leukocytes infected with influenza A virus. J Clin Microbiol 26:1267-70
Abramson, J S (1988) The pathogenesis of bacterial infections in infants and children: the role of viruses. Perspect Biol Med 32:63-72
Abramson, J S; Mills, E L (1988) Depression of neutrophil function induced by viruses and its role in secondary microbial infections. Rev Infect Dis 10:326-41
Caldwell, S E; Cassidy, L F; Abramson, J S (1988) Alterations in cell protein phosphorylation in human neutrophils exposed to influenza A virus. A possible mechanism for depressed cellular end-stage functions. J Immunol 140:3560-7
Abramson, J S; Wheeler, J G; Parce, J W et al. (1986) Suppression of endocytosis in neutrophils by influenza A virus in vitro. J Infect Dis 154:456-63

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