Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI025537-08
Application #
2062989
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-02-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Shelburne, C P; Huff, T F (1999) Inhibition of kit expression in P815 mouse mastocytoma cells by a hammerhead ribozyme. Clin Immunol 93:46-58
Kauma, S W; Huff, T F; Hayes, N et al. (1999) Placental Fas ligand expression is a mechanism for maternal immune tolerance to the fetus. J Clin Endocrinol Metab 84:2188-94
Ryan, J J; DeSimone, S; Klisch, G et al. (1998) IL-4 inhibits mouse mast cell Fc epsilonRI expression through a STAT6-dependent mechanism. J Immunol 161:6915-23
Ryan, J J; Huang, H; McReynolds, L J et al. (1997) Stem cell factor activates STAT-5 DNA binding in IL-3-derived bone marrow mast cells. Exp Hematol 25:357-62
Kauma, S; Huff, T; Krystal, G et al. (1996) The expression of stem cell factor and its receptor, c-kit in human endometrium and placental tissues during pregnancy. J Clin Endocrinol Metab 81:1261-6
Lantz, C S; Huff, T F (1995) Murine KIT+ lineage- bone marrow progenitors express Fc gamma-RII but do not express Fc epsilon-RI until mast cell granule formation. J Immunol 154:355-62
Lantz, C S; Huff, T F (1995) Differential responsiveness of purified mouse c-kit+ mast cells and their progenitors to IL-3 and stem cell factor. J Immunol 155:4024-9
Ryan, J J; Klein, K A; Neuberger, T J et al. (1994) Role for the stem cell factor/KIT complex in Schwann cell neoplasia and mast cell proliferation associated with neurofibromatosis. J Neurosci Res 37:415-32
Plummer 3rd, H; Catlett, J; Leftwich, J et al. (1993) c-myc expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines. Cancer Res 53:4337-42
Leftwich, J A; Westin, E H; Huff, T F (1992) Expression of c-kit by mesenteric lymph node cells from Nippostrongylus brasiliensis-infected mice and by mast cell colonies developing from these cells in response to 3T3 fibroblast-conditioned medium. J Immunol 148:2894-8

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