Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI026126-07
Application #
2063246
Study Section
Virology Study Section (VR)
Project Start
1988-09-30
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Lutz, Gabriel; Jurak, Igor; Kim, Eui Tae et al. (2017) Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors. Viruses 9:
Pan, Dongli; Kaye, Stephen B; Hopkins, Mark et al. (2014) Common and new acyclovir resistant herpes simplex virus-1 mutants causing bilateral recurrent herpetic keratitis in an immunocompetent patient. J Infect Dis 209:345-9
Jurak, Igor; Hackenberg, Michael; Kim, Ju Youn et al. (2014) Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection. J Virol 88:2337-9
Pan, Dongli; Coen, Donald M (2012) Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA. Proc Natl Acad Sci U S A 109:14852-7
Weller, Sandra K; Coen, Donald M (2012) Herpes simplex viruses: mechanisms of DNA replication. Cold Spring Harb Perspect Biol 4:a013011
Pan, Dongli; Coen, Donald M (2012) Quantification and analysis of thymidine kinase expression from acyclovir-resistant G-string insertion and deletion mutants in herpes simplex virus-infected cells. J Virol 86:4518-26
Jurak, Igor; Silverstein, Leah B; Sharma, Mayuri et al. (2012) Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. J Virol 86:10093-102
Jurak, Igor; Griffiths, Anthony; Coen, Donald M (2011) Mammalian alphaherpesvirus miRNAs. Biochim Biophys Acta 1809:641-53
Kramer, Martha F; Jurak, Igor; Pesola, Jean M et al. (2011) Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia. Virology 417:239-47
Kramer, Martha F (2011) Stem-loop RT-qPCR for miRNAs. Curr Protoc Mol Biol Chapter 15:Unit 15.10

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