Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI026941-07
Application #
2063663
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1989-04-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Surgery
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Demaria, S; DeVito-Haynes, L D; Salter, R D et al. (1999) Peptide-conformed beta2m-free class I heavy chains are intermediates in generation of soluble HLA by the membrane-bound metalloproteinase. Hum Immunol 60:1216-26
Burlingham, W J; Jankowska-Gan, E; DeVito-Haynes, L et al. (1998) HLA (A*0201) mimicry by anti-idiotypic monoclonal antibodies. J Immunol 161:6705-14
DeVito-Haynes, L D; Demaria, S; Bushkin, Y et al. (1998) The metalloproteinase-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection. Hum Immunol 59:426-34
O'Herrin, S M; Kulkarni, S; Kenealy, W R et al. (1996) Expression of human recombinant beta 2-microglobulin by Aspergillus nidulans and its activity. Hum Immunol 51:63-72
Burlingham, W J; Grailer, A P; Fechner Jr, J H et al. (1995) Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient. Transplantation 59:1147-55
DeVito-Haynes, L D; Jankowska-Gan, E; Sollinger, H W et al. (1994) Monitoring of kidney and simultaneous pancreas-kidney transplantation rejection by release of donor-specific, soluble HLA class I. Hum Immunol 40:191-201
Geissler, E K; Wang, J; Fechner Jr, J H et al. (1994) Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. J Immunol 152:413-21
DeVito, L D; Hogan, K T; Mason, B P et al. (1993) Epitope fine specificity of human anti-HLA-A2 antibodies. Transplant Proc 25:189-90
Niguma, T; DeVito, L D; Grailer, A P et al. (1993) HLA-A2-specific antibody production in severe combined immunodeficient mice reconstituted with human peripheral blood leukocytes from HLA-presensitized donors. Transplant Proc 25:239-40
De Vito, L D; Mason, B P; Jankowska-Gan, E et al. (1993) Epitope fine specificity of human anti-HLA-A2 antibodies. Identification of four epitopes including a haptenlike epitope on HLA-A2 at lysine 127. Hum Immunol 37:165-77

Showing the most recent 10 out of 19 publications