Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI028018-08
Application #
6488919
Study Section
Special Emphasis Panel (ZRG5-BM-2 (08))
Program Officer
Voulgaropoulou, Frosso
Project Start
1990-07-01
Project End
2004-12-31
Budget Start
2002-01-01
Budget End
2004-12-31
Support Year
8
Fiscal Year
2002
Total Cost
$186,758
Indirect Cost
Name
University of Oklahoma Health Sciences Center
Department
Pathology
Type
Schools of Medicine
DUNS #
937727907
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
Pereira, H Anne; Tsyshevskaya-Hoover, Irina; Hinsley, Heather et al. (2010) Candidacidal activity of synthetic peptides based on the antimicrobial domain of the neutrophil-derived protein, CAP37. Med Mycol 48:263-72
Gordon, Y Jerold; Romanowski, Eric G; Shanks, Robert M Q et al. (2009) CAP37-derived antimicrobial peptides have in vitro antiviral activity against adenovirus and herpes simplex virus type 1. Curr Eye Res 34:241-9
Pereira, H Anne (2006) Novel therapies based on cationic antimicrobial peptides. Curr Pharm Biotechnol 7:229-34
Pereira, H Anne; Ruan, Xin; Gonzalez, Melva L et al. (2004) Modulation of corneal epithelial cell functions by the neutrophil-derived inflammatory mediator CAP37. Invest Ophthalmol Vis Sci 45:4284-92
Gonzalez, Melva L; Ruan, Xin; Kumar, Padmasini et al. (2004) Functional modulation of smooth muscle cells by the inflammatory mediator CAP37. Microvasc Res 67:168-81
Lee, Taunia D; Gonzalez, Melva L; Kumar, Padmasini et al. (2003) CAP37, a neutrophil-derived inflammatory mediator, augments leukocyte adhesion to endothelial monolayers. Microvasc Res 66:38-48
Pereira, H Anne; Ruan, Xin; Kumar, Padmasini (2003) Activation of microglia: a neuroinflammatory role for CAP37. Glia 41:64-72
Ruan, Xin; Chodosh, James; Callegan, Michelle C et al. (2002) Corneal expression of the inflammatory mediator CAP37. Invest Ophthalmol Vis Sci 43:1414-21
Lee, Taunia D; Gonzalez, Melva L; Kumar, Padmasini et al. (2002) CAP37, a novel inflammatory mediator: its expression in endothelial cells and localization to atherosclerotic lesions. Am J Pathol 160:841-8
Pereira, H A (2001) Cationic antimicrobial protein of Mr 37 kDa: a multifunctional inflammatory protein. Chin Med J (Engl) 114:9-13

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