Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029313-07
Application #
2064913
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1990-03-01
Project End
1997-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Pathology
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Clever, J L; Eckstein, D A; Parslow, T G (1999) Genetic dissociation of the encapsidation and reverse transcription functions in the 5' R region of human immunodeficiency virus type 1. J Virol 73:101-9
Clever, J L; Parslow, T G (1997) Mutant human immunodeficiency virus type 1 genomes with defects in RNA dimerization or encapsidation. J Virol 71:3407-14
Lochrie, M A; Waugh, S; Pratt Jr, D G et al. (1997) In vitro selection of RNAs that bind to the human immunodeficiency virus type-1 gag polyprotein. Nucleic Acids Res 25:2902-10
Clever, J L; Wong, M L; Parslow, T G (1996) Requirements for kissing-loop-mediated dimerization of human immunodeficiency virus RNA. J Virol 70:5902-8
Mujeeb, A; Parslow, T G; Yuan, Y C et al. (1996) Aqueous solution structure of a hybrid lentiviral Tat peptide and a model of its interaction with HIV-1 TAR RNA. J Biomol Struct Dyn 13:649-60
Hunter, J J; Bond, B L; Parslow, T G (1996) Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis. Mol Cell Biol 16:877-83
Lee, L C; Hunter, J J; Mujeeb, A et al. (1996) Evidence for alpha-helical conformation of an essential N-terminal region in the human Bcl2 protein. J Biol Chem 271:23284-8
Hunter, J J; Parslow, T G (1996) A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis. J Biol Chem 271:8521-4
Clever, J; Sassetti, C; Parslow, T G (1995) RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1. J Virol 69:2101-9
Elder, M E; Lin, D; Clever, J et al. (1994) Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 264:1596-9

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