Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029857-05
Application #
3144803
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1990-04-01
Project End
1994-06-30
Budget Start
1994-04-01
Budget End
1994-06-30
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Stamatatos, L; Zolla-Pazner, S; Gorny, M K et al. (1997) Binding of antibodies to virion-associated gp120 molecules of primary-like human immunodeficiency virus type 1 (HIV-1) isolates: effect on HIV-1 infection of macrophages and peripheral blood mononuclear cells. Virology 229:360-9
Koito, A; Stamatatos, L; Cheng-Mayer, C (1995) Small amino acid sequence changes within the V2 domain can affect the function of a T-cell line-tropic human immunodeficiency virus type 1 envelope gp120. Virology 206:878-84
Harrowe, G; Cheng-Mayer, C (1995) Amino acid substitutions in the V3 loop are responsible for adaptation to growth in transformed T-cell lines of a primary human immunodeficiency virus type 1. Virology 210:490-4
Stamatatos, L; Cheng-Mayer, C (1995) Structural modulations of the envelope gp120 glycoprotein of human immunodeficiency virus type 1 upon oligomerization and differential V3 loop epitope exposure of isolates displaying distinct tropism upon virion-soluble receptor binding. J Virol 69:6191-8
Koito, A; Harrowe, G; Levy, J A et al. (1994) Functional role of the V1/V2 region of human immunodeficiency virus type 1 envelope glycoprotein gp120 in infection of primary macrophages and soluble CD4 neutralization. J Virol 68:2253-9
Stamatatos, L; Werner, A; Cheng-Mayer, C (1994) Differential regulation of cellular tropism and sensitivity to soluble CD4 neutralization by the envelope gp120 of human immunodeficiency virus type 1. J Virol 68:4973-9
LeGuern, M; Shioda, T; Levy, J A et al. (1993) Single amino acid change in Tat determines the different rates of replication of two sequential HIV-1 isolates. Virology 195:441-7
Stamatatos, L; Cheng-Mayer, C (1993) Evidence that the structural conformation of envelope gp120 affects human immunodeficiency virus type 1 infectivity, host range, and syncytium-forming ability. J Virol 67:5635-9
Cheng-Mayer, C; Shioda, T; Levy, J A (1991) Host range, replicative, and cytopathic properties of human immunodeficiency virus type 1 are determined by very few amino acid changes in tat and gp120. J Virol 65:6931-41
Liu, Z Q; Wood, C; Levy, J A et al. (1990) The viral envelope gene is involved in macrophage tropism of a human immunodeficiency virus type 1 strain isolated from brain tissue. J Virol 64:6148-53