Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI044212-01A1
Application #
2903017
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Heyse, Stephen P
Project Start
1999-06-01
Project End
2004-05-31
Budget Start
1999-06-01
Budget End
2000-05-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Fonseca, Maris V; Sauer, John-Demian; Crepin, Sebastien et al. (2014) The phtC-phtD locus equips Legionella pneumophila for thymidine salvage and replication in macrophages. Infect Immun 82:720-30
Edwards, Rachel L; Bryan, Andrew; Jules, Matthieu et al. (2013) Nicotinic acid modulates Legionella pneumophila gene expression and induces virulence traits. Infect Immun 81:945-55
Dalebroux, Zachary D; Swanson, Michele S (2012) ppGpp: magic beyond RNA polymerase. Nat Rev Microbiol 10:203-12
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Bryan, Andrew; Swanson, Michele S (2011) Oligonucleotides stimulate genomic alterations of Legionella pneumophila. Mol Microbiol 80:231-47
Hilbi, Hubert; Jarraud, Sophie; Hartland, Elizabeth et al. (2010) Update on Legionnaires' disease: pathogenesis, epidemiology, detection and control. Mol Microbiol 76:1-11
Tiaden, André; Spirig, Thomas; Sahr, Tobias et al. (2010) The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila. Environ Microbiol 12:1243-59
Dalebroux, Zachary D; Yagi, Brian F; Sahr, Tobias et al. (2010) Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation. Mol Microbiol 76:200-19
Edwards, Rachel L; Jules, Matthieu; Sahr, Tobias et al. (2010) The Legionella pneumophila LetA/LetS two-component system exhibits rheostat-like behavior. Infect Immun 78:2571-83
Dalebroux, Zachary D; Svensson, Sarah L; Gaynor, Erin C et al. (2010) ppGpp conjures bacterial virulence. Microbiol Mol Biol Rev 74:171-99

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