Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI046164-03
Application #
6374285
Study Section
Special Emphasis Panel (ZRG1-VACC (01))
Program Officer
Butler, Robert C
Project Start
1999-06-01
Project End
2003-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
3
Fiscal Year
2001
Total Cost
$284,654
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Sadler, Kristen; Eom, Khee Dong; Yang, Jin-Long et al. (2002) Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7. Biochemistry 41:14150-7
Tam, James P; Lu, Yi-An; Yang, Jin-Long (2002) Antimicrobial dendrimeric peptides. Eur J Biochem 269:923-32
Tam, James P; Lu, Yi-An; Yang, Jin-Long (2002) Correlations of cationic charges with salt sensitivity and microbial specificity of cystine-stabilized beta -strand antimicrobial peptides. J Biol Chem 277:50450-6
Sun, Y; Lu, G; Tam, J P (2001) A thioester ligation approach to amphipathic bicyclic peptide library. Org Lett 3:1681-4
Tam, J P; Wu, C; Yang, J L (2000) Membranolytic selectivity of cystine-stabilized cyclic protegrins. Eur J Biochem 267:3289-300
Yu, Q; Lehrer, R I; Tam, J P (2000) Engineered salt-insensitive alpha-defensins with end-to-end circularized structures. J Biol Chem 275:3943-9
Tam, J P; Lu, Y A; Yang, J L (2000) Marked increase in membranolytic selectivity of novel cyclic tachyplesins constrained with an antiparallel two-beta strand cystine knot framework. Biochem Biophys Res Commun 267:783-90
Tam, J P; Lu, Y A; Yang, J L (2000) Design of salt-insensitive glycine-rich antimicrobial peptides with cyclic tricystine structures. Biochemistry 39:7159-69
Li, X; Zhang, L; Zhang, W et al. (2000) Solid-phase synthesis of 1,2,3, 4-tetrahydro-beta-carboline-containing peptidomimetics. Org Lett 2:3075-8
Chang, M S; Tam, J P; Sanders-Bush, E (2000) Dissecting intracellular signaling pathways with membrane-permeable peptides. Sci STKE 2000:pl1

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