Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI124355-03
Application #
9225158
Study Section
Special Emphasis Panel (ZAI1-LAR-I (J1))
Program Officer
Minnicozzi, Michael
Project Start
2015-09-01
Project End
2020-02-29
Budget Start
2017-03-01
Budget End
2018-02-28
Support Year
3
Fiscal Year
2017
Total Cost
$555,000
Indirect Cost
$199,231
Name
Cincinnati Children's Hospital Medical Center
Department
Type
Independent Hospitals
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Litosh, Vladislav A; Rochman, Mark; Rymer, Jeffrey K et al. (2017) Calpain-14 and its association with eosinophilic esophagitis. J Allergy Clin Immunol 139:1762-1771.e7
Kottyan, L C; Rothenberg, M E (2017) Genetics of eosinophilic esophagitis. Mucosal Immunol 10:580-588
Rochman, Mark; Travers, Jared; Miracle, Cora E et al. (2017) Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis. J Allergy Clin Immunol 140:738-749.e3
O'Shea, Kelly M; Aceves, Seema S; Dellon, Evan S et al. (2017) Pathophysiology of Eosinophilic Esophagitis. Gastroenterology :
Abonia, J Pablo; Spergel, Jonathan M; Cianferoni, Antonella (2017) Eosinophilic Esophagitis: A Primary Disease of the Esophageal Mucosa. J Allergy Clin Immunol Pract 5:951-955
Travers, J; Rochman, M; Caldwell, J M et al. (2017) IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis. Sci Rep 7:17563
Jensen, Elizabeth T; Kuhl, Jonathan T; Martin, Lisa J et al. (2017) Early-life environmental exposures interact with genetic susceptibility variants in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol :
Wen, Ting; Rothenberg, Marc E (2017) Clinical Applications of the Eosinophilic Esophagitis Diagnostic Panel. Front Med (Lausanne) 4:108
Davis, Benjamin P; Stucke, Emily M; Khorki, M Eyad et al. (2016) Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI Insight 1:e86355
Travers, Jared; Rochman, Mark; Miracle, Cora E et al. (2016) Linking impaired skin barrier function to esophageal allergic inflammation via IL-33. J Allergy Clin Immunol 138:1381-1383

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