Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR032927-12
Application #
2078889
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1984-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Washington University
Department
Physiology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Collin-Osdoby, Patricia; Osdoby, Philip (2012) Isolation and culture of primary chicken osteoclasts. Methods Mol Biol 816:119-43
Collin-Osdoby, Patricia; Osdoby, Philip (2012) RANKL-mediated osteoclast formation from murine RAW 264.7 cells. Methods Mol Biol 816:187-202
Collin-Osdoby, Patricia; Yu, Xuefeng; Zheng, Hong et al. (2003) RANKL-mediated osteoclast formation from murine RAW 264.7 cells. Methods Mol Med 80:153-66
Collin-Osdoby, Patricia; Anderson, Fred; Osdoby, Philip (2003) Primary isolation and culture of chicken osteoclasts. Methods Mol Med 80:65-88
Yu, Xuefeng; Huang, Yuefang; Collin-Osdoby, Patricia et al. (2003) Stromal cell-derived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration. J Bone Miner Res 18:1404-18
Collin-Osdoby, Patricia; Rothe, Linda; Bekker, Simon et al. (2002) Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro. J Bone Miner Res 17:1859-71
Collin-Osdoby, P; Rothe, L; Anderson, F et al. (2001) Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis. J Biol Chem 276:20659-72
Collin-Osdoby, P; Rothe, L; Bekker, S et al. (2000) Decreased nitric oxide levels stimulate osteoclastogenesis and bone resorption both in vitro and in vivo on the chick chorioallantoic membrane in association with neoangiogenesis. J Bone Miner Res 15:474-88
Collin-Osdoby, P; Li, L; Rothe, L et al. (1998) Inhibition of avian osteoclast bone resorption by monoclonal antibody 121F: a mechanism involving the osteoclast free radical system. J Bone Miner Res 13:67-78
Khalkhali-Ellis, Z; Collin-Osdoby, P; Li, L et al. (1997) A human homolog of the 150 kD avian osteoclast membrane antigen related to superoxide dismutase and essential for bone resorption is induced by developmental agents and opposed by estrogen in FLG 29.1 cells. Calcif Tissue Int 60:187-93

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