Control of Type X Collagen Gene Expression

Pacifici, Maurizio

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 5R01AR039705-04
• Application #: 3159911
• Study Section: Pathobiochemistry Study Section (PBC)
• Project Start: 1989-02-01
• Project End: 1994-01-31
• Budget Start: 1992-02-01
• Budget End: 1993-01-31
• Support Year: 4
• Fiscal Year: 1992

Institution

• Name: University of Pennsylvania
• Type: Schools of Dentistry
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Iwamoto, M; Yagami, K; Shapiro, I M et al. (1994) Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization. Microsc Res Tech 28:483-91

Lu Valle, P; Iwamoto, M; Fanning, P et al. (1993) Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. J Cell Biol 121:1173-9

Iwamoto, M; Shapiro, I M; Yagami, K et al. (1993) Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes. Exp Cell Res 207:413-20

Iwamoto, M; Golden, E B; Adams, S L et al. (1993) Responsiveness to retinoic acid changes during chondrocyte maturation. Exp Cell Res 205:213-24

Iwamoto, M; Yagami, K; Lu Valle, P et al. (1993) Expression and role of c-myc in chondrocytes undergoing endochondral ossification. J Biol Chem 268:9645-52

Adams, S L; Pallante, K M; Niu, Z et al. (1991) Rapid induction of type X collagen gene expression in cultured chick vertebral chondrocytes. Exp Cell Res 193:190-7

Pacifici, M; Golden, E B; Adams, S L et al. (1991) Cell hypertrophy and type X collagen synthesis in cultured articular chondrocytes. Exp Cell Res 192:266-70

Shapiro, I M; Leboy, P S; Tokuoka, T et al. (1991) Ascorbic acid regulates multiple metabolic activities of cartilage cells. Am J Clin Nutr 54:1209S-1213S

Pacifici, M; Golden, E B; Oshima, O et al. (1990) Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage? Ann N Y Acad Sci 599:45-57

Adams, S L (1989) Collagen gene expression. Am J Respir Cell Mol Biol 1:161-8