Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR040620-07
Application #
2080173
Study Section
Special Emphasis Panel (ZRG4-GMA-2 (01))
Project Start
1990-06-30
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sekiguchi, Debora R; Jainandunsing, Sandra M; Fields, Michele L et al. (2002) Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J Immunol 168:4142-53
Maldonado, M A; MacDonald, G C; Kakkanaiah, V N et al. (1999) Differential control of autoantibodies and lymphoproliferation by Fas ligand expression on CD4+ and CD8+ T cells in vivo. J Immunol 163:3138-42
Firestein, R; Feuerstein, N (1998) Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9. Implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells. J Biol Chem 273:5892-902
Kakkanaiah, V N; Sobel, E S; MacDonald, G C et al. (1997) B cell genotype determines the fine specificity of autoantibody in lpr mice. J Immunol 159:1027-35
Creech, E A; Nakul-Aquaronne, D; Reap, E A et al. (1996) MHC genes modify systemic autoimmune disease. The role of the I-E locus. J Immunol 156:812-7
Kakkanaiah, V N; MacDonald, G C; Cohen, P L et al. (1996) Suppression and reversal of gld disease by parabiosis with normal mice. Clin Immunol Immunopathol 78:6-13
Reap, E A; Piecyk, M L; Oliver, A et al. (1996) Phenotypic abnormalities of splenic and bone marrow B cells in lpr and gld mice. Clin Immunol Immunopathol 78:21-9
Sobel, E S; Kakkanaiah, V N; Rapoport, R G et al. (1995) The abnormal lpr double-negative T cell fails to proliferate in vivo. Clin Immunol Immunopathol 74:177-84
MacDonald, G C; Kakkanaiah, V N; Sobel, E S et al. (1995) In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras. J Immunol 154:444-9
Reap, E A; Leslie, D; Abrahams, M et al. (1995) Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. J Immunol 154:936-43

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