Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR047838-03
Application #
6787706
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Program Officer
Sharrock, William J
Project Start
2002-07-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
3
Fiscal Year
2004
Total Cost
$629,735
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Bajaj, Devendra; Geissler, Joseph R; Allen, Matthew R et al. (2016) Response to Courtney et al. Bone 89:77-79
Burr, David B; Liu, Ziyue; Allen, Matthew R (2015) Duration-dependent effects of clinically relevant oral alendronate doses on cortical bone toughness in beagle dogs. Bone 71:58-62
Acevedo, Claire; Bale, Hrishikesh; Gludovatz, Bernd et al. (2015) Alendronate treatment alters bone tissues at multiple structural levels in healthy canine cortical bone. Bone 81:352-363
Gallant, Maxime A; Brown, Drew M; Hammond, Max et al. (2014) Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone 61:191-200
Bajaj, Devendra; Geissler, Joseph R; Allen, Matthew R et al. (2014) The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate. Bone 64:57-64
Hill Gallant, Kathleen M; Gallant, Maxime A; Brown, Drew M et al. (2014) Raloxifene prevents skeletal fragility in adult female Zucker Diabetic Sprague-Dawley rats. PLoS One 9:e108262
Gonzalez, Armando Diaz; Gallant, Maxime A; Burr, David B et al. (2014) Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes. J Biomech 47:681-6
Hammond, Max A; Gallant, Maxime A; Burr, David B et al. (2014) Nanoscale changes in collagen are reflected in physical and mechanical properties of bone at the microscale in diabetic rats. Bone 60:26-32
Gallant, Maxime A; Brown, Drew M; Organ, Jason M et al. (2013) Reference-point indentation correlates with bone toughness assessed using whole-bone traditional mechanical testing. Bone 53:301-5
Green, J O; Diab, T; Allen, M R et al. (2012) Three years of alendronate treatment does not continue to decrease microstructural stresses and strains associated with trabecular microdamage initiation beyond those at 1 year. Osteoporos Int 23:2313-20

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