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Eliopoulos, Aristides G; Das, Santasabuj; Tsichlis, Philip N (2006) The tyrosine kinase Syk regulates TPL2 activation signals. J Biol Chem 281:1371-80
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Cho, Jeonghee; Tsichlis, Philip N (2005) Phosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide. Proc Natl Acad Sci U S A 102:2350-5
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Cho, Jeonghee; Melnick, Michael; Solidakis, Georgios P et al. (2005) Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals. J Biol Chem 280:20442-8
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Das, Santasabuj; Cho, Jeonghee; Lambertz, Irina et al. (2005) Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner. J Biol Chem 280:23748-57
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Eliopoulos, Aristides G; Wang, Chun-Chi; Dumitru, Calin D et al. (2003) Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40. EMBO J 22:3855-64
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Eliopoulos, Aristides G; Dumitru, Calin D; Wang, Chun-Chi et al. (2002) Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals. EMBO J 21:4831-40
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Kontoyiannis, Dimitris; Boulougouris, George; Manoloukos, Menelaos et al. (2002) Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease. J Exp Med 196:1563-74
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Eliopoulos, Aristides G; Davies, Clare; Blake, Sarah S M et al. (2002) The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2. J Virol 76:4567-79
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Chan, T O; Tsichlis, P N (2001) PDK2: a complex tail in one Akt. Sci STKE 2001:pe1
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Patriotis, C; Russeva, M G; Lin, J H et al. (2001) Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3. J Cell Physiol 187:176-87
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