Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA038701-10S1
Application #
2089626
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1985-08-01
Project End
1998-11-30
Budget Start
1994-12-29
Budget End
1995-11-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Läubli, Heinz; Varki, Ajit; Borsig, Lubor (2016) Antimetastatic Properties of Low Molecular Weight Heparin. J Clin Oncol 34:2560-1
Schwarz, Flavio; Fong, Jerry J; Varki, Ajit (2015) Human-specific evolutionary changes in the biology of siglecs. Adv Exp Med Biol 842:1-16
Samraj, Annie N; Pearce, Oliver M T; Läubli, Heinz et al. (2015) A red meat-derived glycan promotes inflammation and cancer progression. Proc Natl Acad Sci U S A 112:542-7
Varki, Nissi M; Varki, Ajit (2015) On the apparent rarity of epithelial cancers in captive chimpanzees. Philos Trans R Soc Lond B Biol Sci 370:
Samraj, Annie N; Läubli, Heinz; Varki, Nissi et al. (2014) Involvement of a non-human sialic Acid in human cancer. Front Oncol 4:33
Chang, Yung-Chi; Olson, Joshua; Beasley, Federico C et al. (2014) Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo. PLoS Pathog 10:e1003846
Pearce, Oliver Mt; Läubli, Heinz; Bui, Jack et al. (2014) Hormesis in cancer immunology: Does the quantity of an immune reactant matter? Oncoimmunology 3:e29312
Läubli, Heinz; Pearce, Oliver M T; Schwarz, Flavio et al. (2014) Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer. Proc Natl Acad Sci U S A 111:14211-6
Deng, Lingquan; Song, Jeongmin; Gao, Xiang et al. (2014) Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. Cell 159:1290-9
Pearce, Oliver M T; Läubli, Heinz; Verhagen, Andrea et al. (2014) Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. Proc Natl Acad Sci U S A 111:5998-6003

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