Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA049240-07A2
Application #
2093216
Study Section
Pathology B Study Section (PTHB)
Project Start
1989-01-01
Project End
2000-06-30
Budget Start
1996-09-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Guttridge, Katherine L; Luft, J Christopher; Dawson, Thomas L et al. (2002) Mer receptor tyrosine kinase signaling: prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation. J Biol Chem 277:24057-66
Burchert, A; Attar, E C; McCloskey, P et al. (1998) Determinants for transformation induced by the Axl receptor tyrosine kinase. Oncogene 16:3177-87
Fridell, Y W; Villa Jr, J; Attar, E C et al. (1998) GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cells. J Biol Chem 273:7123-6
Fridell, Y W; Jin, Y; Quilliam, L A et al. (1996) Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase. Mol Cell Biol 16:135-45
O'Bryan, J P; Fridell, Y W; Koski, R et al. (1995) The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage. J Biol Chem 270:551-7
Neubauer, A; Dodge, R K; George, S L et al. (1994) Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood 83:1603-11
Neubauer, A; Greenberg, P; Negrin, R et al. (1994) Mutations in the ras proto-oncogenes in patients with myelodysplastic syndromes. Leukemia 8:638-41
Neubauer, A; Fiebeler, A; Graham, D K et al. (1994) Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis. Blood 84:1931-41
McCloskey, P; Pierce, J; Koski, R A et al. (1994) Activation of the Axl receptor tyrosine kinase induces mitogenesis and transformation in 32D cells. Cell Growth Differ 5:1105-17
Neubauer, A; He, M; Schmidt, C A et al. (1993) Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques. Leukemia 7:593-600

Showing the most recent 10 out of 19 publications