Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA052047-01A3S1
Application #
3196813
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1992-07-01
Project End
1996-04-30
Budget Start
1992-07-01
Budget End
1993-04-30
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Chen, Aiping; Weber, Irene T; Harrison, Robert W et al. (2006) Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends. J Biol Chem 281:4173-82
Medina, Gisselle; Zhang, Yongjun; Tang, Yi et al. (2005) The functionally exchangeable L domains in RSV and HIV-1 Gag direct particle release through pathways linked by Tsg101. Traffic 6:880-94
Vana, Marcy L; Chen, Aiping; Boross, Peter et al. (2005) Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication. Retrovirology 2:58
Vana, Marcy L; Tang, Yi; Chen, Aiping et al. (2004) Role of Nedd4 and ubiquitination of Rous sarcoma virus Gag in budding of virus-like particles from cells. J Virol 78:13943-53
Johnson, Michael; Morris, Shannon; Chen, Aiping et al. (2004) Selection of functional mutations in the U5-IR stem and loop regions of the Rous sarcoma virus genome. BMC Biol 2:8
Brin, Elena; Leis, Jonathan (2002) HIV-1 integrase interaction with U3 and U5 terminal sequences in vitro defined using substrates with random sequences. J Biol Chem 277:18357-64
Brin, Elena; Leis, Jonathan (2002) Changes in the mechanism of DNA integration in vitro induced by base substitutions in the HIV-1 U5 and U3 terminal sequences. J Biol Chem 277:10938-48
Morris, Shannon; Johnson, Michael; Stavnezer, Ed et al. (2002) Replication of avian sarcoma virus in vivo requires an interaction between the viral RNA and the TpsiC loop of the tRNA(Trp) primer. J Virol 76:7571-7
Mayo, Keith; Vana, Marcy L; McDermott, Jason et al. (2002) Analysis of Rous sarcoma virus capsid protein variants assembled on lipid monolayers. J Mol Biol 316:667-78
VerPlank, L; Bouamr, F; LaGrassa, T J et al. (2001) Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc Natl Acad Sci U S A 98:7724-9

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