Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA058841-03
Application #
2099468
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1993-07-12
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Dermatology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Rook, A H; Suchin, K R; Kao, D M et al. (1999) Photopheresis: clinical applications and mechanism of action. J Investig Dermatol Symp Proc 4:85-90
Fox, F E; Kubin, M; Cassin, M et al. (1999) Retinoids synergize with interleukin-2 to augment IFN-gamma and interleukin-12 production by human peripheral blood mononuclear cells. J Interferon Cytokine Res 19:407-15
Li, G; Chooback, L; Wolfe, J T et al. (1998) Overexpression of p53 protein in cutaneous T cell lymphoma: relationship to large cell transformation and disease progression. J Invest Dermatol 110:767-70
Li, G; Salhany, K E; Rook, A H et al. (1997) The pathogenesis of large cell transformation in cutaneous T-cell lymphoma is not associated with t(2;5)(p23;q35) chromosomal translocation. J Cutan Pathol 24:403-8
Rook, A H; Gottlieb, S L; Wolfe, J T et al. (1997) Pathogenesis of cutaneous T-cell lymphoma: implications for the use of recombinant cytokines and photopheresis. Clin Exp Immunol 107 Suppl 1:16-20
Yoo, E K; Rook, A H; Elenitsas, R et al. (1996) Apoptosis induction of ultraviolet light A and photochemotherapy in cutaneous T-cell Lymphoma: relevance to mechanism of therapeutic action. J Invest Dermatol 107:235-42
Rook, A H; Kubin, M; Fox, F E et al. (1996) The potential therapeutic role of interleukin-12 in cutaneous T-cell lymphoma. Ann N Y Acad Sci 795:310-8
Li, G; Vowels, B R; Benoit, B M et al. (1996) Failure to detect human T-lymphotropic virus type-I proviral DNA in cell lines and tissues from patients with cutaneous T-cell lymphoma. J Invest Dermatol 107:308-13
Weinberg, J M; Jaworsky, C; Benoit, B M et al. (1995) The clonal nature of circulating Sezary cells. Blood 86:4257-62
Wolfe, J T; Chooback, L; Finn, D T et al. (1995) Large-cell transformation following detection of minimal residual disease in cutaneous T-cell lymphoma: molecular and in situ analysis of a single neoplastic T-cell clone expressing the identical T-cell receptor. J Clin Oncol 13:1751-7

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