Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060945-04
Application #
2101712
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1993-08-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Singh, Shivendra V; Herman-Antosiewicz, Anna; Singh, Ajita V et al. (2004) Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. J Biol Chem 279:25813-22
Klint, Peter; Hellman, Ulf; Wernstedt, Christer et al. (2004) Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1. Cell Signal 16:515-20
Bertolotti, A; Wang, X; Novoa, I et al. (2001) Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest 107:585-93
Kuroda, M; Sok, J; Webb, L et al. (2000) Male sterility and enhanced radiation sensitivity in TLS(-/-) mice. EMBO J 19:453-62
Kanoe, H; Nakayama, T; Hosaka, T et al. (1999) Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation. Oncogene 18:721-9
Baechtold, H; Kuroda, M; Sok, J et al. (1999) Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation. J Biol Chem 274:34337-42
Kuroda, M; Wang, X; Sok, J et al. (1999) Induction of a secreted protein by the myxoid liposarcoma oncogene. Proc Natl Acad Sci U S A 96:5025-30
Wang, X Z; Jolicoeur, E M; Conte, N et al. (1999) gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line. Oncogene 18:5718-21
Wang, X Z; Kuroda, M; Sok, J et al. (1998) Identification of novel stress-induced genes downstream of chop. EMBO J 17:3619-30
Powers, C A; Mathur, M; Raaka, B M et al. (1998) TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors. Mol Endocrinol 12:4-18

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