Smoking remains the leading preventable cause of death, accounting for one-third of all cancers and nearly two-thirds of heart disease among people under 55. Reducing tobacco-induced disease requires understanding how the tobacco industry maintains a social and policy environment favorable to smoking. To understand a microbe, one might study its genome;the tobacco industry's "genome" is its written record of research and decision making in the form of over 83 million pages of previously secret internal tobacco industry documents. We will use this growing collection of industry documents, triangulated with data from other sources, to pursue four Specific Aims: (1) Analyze tobacco industry internal research to gain a better understanding of how and why the tobacco companies promote some metrics of tobacco product toxicity and avoid others in the context of regulation of tobacco products and assessment of "reduced harm" and nicotine replacement products;(2) Use the tobacco industry's internal research to gain a better understanding of how packaging elements, including color, font, and other aspects of packaging influence consumers'perceptions of the cigarettes contained in the packages, (3) Understand tobacco industry analyses of marketing and development of "other non-cigarette tobacco products" (e.g. little cigars/cigarillos, hookah, roll your own cigarettes), nicotine replacement, and nicotine delivery devices such as e-cigarettes, including the impact of their use on cigarette use;and (4) Analyze evolving tobacco industry strategies to oppose tobacco control policies at the local, state, national, and international level, including efforts to undermine implementation of the World Health Organization Framework Convention on Tobacco Control. While this research makes systematic use of digitized tobacco industry documents as the primary data source, we will also triangulate with other sources (including government records, advertising archives, media coverage of issues discussed in the documents, the academic literature, and interviews with key informants) to confirm whether plans described in the documents were actually implemented and to assess their effect. The research questions we propose are innovative because they address the latest activities of tobacco companies in the rapidly evolving policy and regulatory framework for tobacco products. Results of this research will inform the development of more effective tobacco control strategies, which will help reduce tobacco use and its associated burden of cancer and other tobacco-caused disease and death.

Public Health Relevance

Smoking is the leading preventable cause of death, accounting for 1/3 of all cancers and nearly 2/3 of heart disease among people under 55. Reducing this burden of disease requires understanding how the tobacco industry maintains a favorable social and policy environment to promote smoking so that public health professionals can develop and implement effective programs to prevent smoking and promote cessation.

National Institute of Health (NIH)
Research Project (R01)
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Study Section
Community Influences on Health Behavior (CIHB)
Program Officer
Kaufman, Annette R
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University of California San Francisco
Internal Medicine/Medicine
Schools of Medicine
San Francisco
United States
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Velicer, Clayton; Lempert, Lauren K; Glantz, Stanton (2015) Cigarette company trade secrets are not secret: an analysis of reverse engineering reports in internal tobacco industry documents released as a result of litigation. Tob Control 24:469-80
Fallin, Amanda; Grana, Rachel; Glantz, Stanton A (2014) 'To quarterback behind the scenes, third-party efforts': the tobacco industry and the Tea Party. Tob Control 23:322-31
Jiang, Nan; Lee, Youn Ok; Ling, Pamela M (2014) Association between tobacco and alcohol use among young adult bar patrons: a cross-sectional study in three cities. BMC Public Health 14:500
Crosbie, Eric; Gonzalez, Mariaelena; Glantz, Stanton A (2014) Health preemption behind closed doors: trade agreements and fast-track authority. Am J Public Health 104:e7-e13
Laposata, Elizabeth; Kennedy, Allison P; Glantz, Stanton A (2014) When tobacco targets direct democracy. J Health Polit Policy Law 39:537-64
Barry, Rachel Ann; Hiilamo, Heikki; Glantz, Stanton A (2014) Waiting for the opportune moment: the tobacco industry and marijuana legalization. Milbank Q 92:207-42
Brown-Johnson, Cati G; England, Lucinda J; Glantz, Stanton A et al. (2014) Tobacco industry marketing to low socioeconomic status women in the U.S.A. Tob Control 23:e139-46
Ling, Pamela M; Lee, Youn Ok; Hong, Juliette et al. (2014) Social branding to decrease smoking among young adults in bars. Am J Public Health 104:751-60
Song, Anna V; Brown, Paul; Glantz, Stanton A (2014) When health policy and empirical evidence collide: the case of cigarette package warning labels and economic consumer surplus. Am J Public Health 104:e42-51
Lee, Youn Ok; Bahreinifar, Sareh; Ling, Pamela M (2014) Understanding tobacco-related attitudes among college and noncollege young adult hookah and cigarette users. J Am Coll Health 62:10-8

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