? The purpose of this multi-method cross-sectional study is to identify health-related Quality of Life (HR-QOL) concerns specific to long-term colorectal cancer survivors (> 5 years from diagnosis) with intestinal stomas and relate those concerns to underlying disease state, time with stoma, comorbidities, as well as other demographic characteristics such as age, gender, and ethnicity. In addition, the skills and methods of adaptation to ostomies, as well as persisting challenges will be explored to gather insights about potential interventions that may be useful to improving HR-QOL for these patients. Long-term objectives are to generate targeted innovative psychosocial interventions designed to facilitate adaptation to stomal challenges and factors impinging on HR-QOL in long-term colorectal cancer survivors with stomas. Based on study results, a program of research will be developed to test interventions. Study methods will include collection of HR-QOL data using well-validated instruments in a mailed survey of long-term (> 5 years after diagnosis) colorectal cancer survivors with and without ostomies who are in care in two large, multiethnic Kaiser Permanente regions. Following completion of the survey, focus groups will be held, separate for men and women, to investigate the coping skills and barriers for those in the highest and lowest quartiles of HR-QOL. The final step will be to convene provider investigators to make recommendations for future interventions and dissemination methods based upon study findings. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA106912-03
Application #
7114397
Study Section
Special Emphasis Panel (ZCA1-SRRB-Y (F1))
Program Officer
Aziz, Noreen M
Project Start
2004-09-15
Project End
2008-08-31
Budget Start
2006-09-01
Budget End
2008-08-31
Support Year
3
Fiscal Year
2006
Total Cost
$376,997
Indirect Cost
Name
University of Arizona
Department
Surgery
Type
Schools of Medicine
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Bulkley, Joanna E; McMullen, Carmit K; Grant, Marcia et al. (2018) Ongoing ostomy self-care challenges of long-term rectal cancer survivors. Support Care Cancer 26:3933-3939
Sun, Virginia; Wendel, Christopher S; Demark-Wahnefried, Wendy et al. (2018) Diet and Behavior Modifications by Long-term Rectal Cancer Survivors to Manage Bowel Dysfunction-Associated Symptoms. Nutr Cancer :1-11
Alavi, Mubarika; Wendel, Christopher S; Krouse, Robert S et al. (2017) Predictors of Bowel Function in Long-term Rectal Cancer Survivors with Anastomosis. Ann Surg Oncol 24:3596-3603
Mcmullen, Carmit; Liu, Liyan; Bulkley, Joanna E et al. (2017) Participation in Activities Associated With Quality of Life for Long-Term Survivors of Rectal Cancer. Perm J 21:
Hornbrook, Mark C; Grant, Marcia; Wendel, Christopher et al. (2017) Rectal Cancer Survivors' Participation in Productive Activities. Perm J 22:
Krouse, Robert S; Wendel, Christopher S; Garcia, David O et al. (2017) Physical activity, bowel function, and quality of life among rectal cancer survivors. Qual Life Res 26:3131-3142
McMullen, Carmit K; Bulkley, Joanna E; Altschuler, Andrea et al. (2016) Greatest Challenges of Rectal Cancer Survivors: Results of a Population-Based Survey. Dis Colon Rectum 59:1019-1027
Herrinton, Lisa J; Altschuler, Andrea; McMullen, Carmit K et al. (2016) Conversations for providers caring for patients with rectal cancer: Comparison of long-term patient-centered outcomes for patients with low rectal cancer facing ostomy or sphincter-sparing surgery. CA Cancer J Clin 66:387-97
Sun, Virginia; Grant, Marcia; Wendel, Christopher S et al. (2016) Sexual Function and Health-Related Quality of Life in Long-Term Rectal Cancer Survivors. J Sex Med 13:1071-9
Chongpison, Yuda; Hornbrook, Mark C; Harris, Robin B et al. (2016) Self-reported depression and perceived financial burden among long-term rectal cancer survivors. Psychooncology 25:1350-1356

Showing the most recent 10 out of 29 publications