Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA157268-05S1
Application #
9079771
Study Section
Special Emphasis Panel (ZRG1-OBT-Z (02))
Program Officer
Lin, Alison J
Project Start
2011-09-01
Project End
2016-07-31
Budget Start
2015-08-01
Budget End
2016-07-31
Support Year
5
Fiscal Year
2015
Total Cost
$67,263
Indirect Cost
$21,297
Name
Duke University
Department
Genetics
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Nicholson, Cindo O; Friedersdorf, Matthew; Keene, Jack D (2017) Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq. RNA 23:32-46
Nicholson, Cindo O; Friedersdorf, Matthew B; Bisogno, Laura S et al. (2017) DO-RIP-seq to quantify RNA binding sites transcriptome-wide. Methods 118-119:16-23
Smola, Matthew J; Christy, Thomas W; Inoue, Kaoru et al. (2016) SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells. Proc Natl Acad Sci U S A 113:10322-7
Blackinton, Jeff G; Keene, Jack D (2016) Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation. Nucleic Acids Res 44:426-36
Moon, Stephanie L; Blackinton, Jeffrey G; Anderson, John R et al. (2015) XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability. PLoS Pathog 11:e1004708
Jiang, Huifeng; Xu, Lin; Wang, Zhe et al. (2014) Coordinating expression of RNA binding proteins with their mRNA targets. Sci Rep 4:7175
Friedersdorf, Matthew B; Keene, Jack D (2014) Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs. Genome Biol 15:R2
Payne, Tamika L; Blackinton, Jeff; Frisbee, Alyse et al. (2014) Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. J Virol 88:9514-28
Blackinton, Jeff G; Keene, Jack D (2014) Post-transcriptional RNA regulons affecting cell cycle and proliferation. Semin Cell Dev Biol 34:44-54
Keene, Jack D (2014) The globalization of messenger RNA regulation. Natl Sci Rev 1:184-186

Showing the most recent 10 out of 12 publications