Tobacco use behavior is complex and changing, with electronic cigarettes (e-cigarettes) increasing in use. In the face of these changes, we need to know more about the behavioral phenomenon of e-cigarette use and its association with other factors, such as continued combustible tobacco use (conventional cigarettes), nicotine dependence, or changes in patterns of tobacco product use, including reductions or cessation of conventional cigarettes and uptake of e-cigarettes. Understanding e-cigarettes, as they are actually used, will help guide the FDA in their regulatory decisions. This project will use Ecological Momentary Assessments (EMA) to gather real-time reports of dual product (both conventional and e-cigarette) users' daily experiences and tobacco use to examine how the immediate context of tobacco use, along with the individual's subjective reactions to those experiences, varies by product and individual characteristics, and influences future patterns of conventional and e-cigarette use. We address several FDA research priorities: 1) the diversity of tobacco use behavior and associated attitudes, perceptions, and subjective experiences; 2) how subjective experiences associated with the use of diverse tobacco products are associated with tobacco dependence and changes in dependence; and 3) how awareness of e-cigarette messages is associated with expectancies and experiences surrounding e-cigarette use. We will recruit 450 adult cigarette smokers who also use or who are at high risk for using e-cigarettes and conduct two longitudinal waves of EMA.
Our aims i nclude: 1) examining the micro-contexts of tobacco use and how they vary by product and individual differences (e.g., demographics, tobacco history, dependence) in order to understand better the functional value of e-cigarettes; 2) examining real-time withdrawal, cravings, and satisfaction with tobacco products and how these affect transitions in tobacco use; and 3) examining how proximal tobacco cues relate to tobacco use experiences, contexts, and patterns of use. Our in-depth examination of the real-time reactions to the use of e-cigarettes directly addresses FDA questions of interest.

Public Health Relevance

This project addresses several research gaps that will help inform the FDA Center for Tobacco Product's (CTP) regulatory mission, including understanding more about the diversity of tobacco products; how use of these products may affect and reduce addiction; and the cognitive and affective factors associated with their use. This project, with it in-depth focus on the functional value and subjective experience of using electronic cigarettes, will help support the CTP regulatory decisions on how use of noncombusted products influences tobacco use patterns and has implications for the public health.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA184681-03
Application #
9327964
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Augustson, Erik
Project Start
2015-08-10
Project End
2020-07-31
Budget Start
2017-08-01
Budget End
2018-07-31
Support Year
3
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612