Digital breast tomosynthesis (DBT) has been shown to significantly increase accuracy in the early detection and diagnosis of breast cancer. The goals of this proposal are to further enhance the efficacy and performance of this type of imaging by removing mechanical motion of the X-ray tube through the development of a stationary X-ray source DBT system. The development of a stationary X-ray source DBT system will enable a 3- to over 10-fold decrease in scan time relative to that of existing commercial systems. Shorter scan times improve image quality by reducing instances of patient motion without introducing image blurring due to tube movement or vibration ? keys to exploiting the improved imaging sensitivity of DBT. In addition, it is anticipated that the proposed system could expand the availability of DBT by decreasing up-front capital, operating, and maintenance costs. We expect that lower-cost, higher-performance imaging will accelerate the on-going displacement of full-field digital mammography by DBT, thereby providing more women with higher quality imaging sooner.

Public Health Relevance

Digital breast tomosynthesis (DBT) has been shown to improve accuracy in the early detection and diagnosis of breast cancer. The goal of the proposed research is to construct and quantify the performance of a stationary X-ray source DBT system that improves the efficacy and performance of this type of imaging by reducing scan times, enhancing image quality, and decreasing the size and cost of the imaging system.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA214515-01
Application #
9287706
Study Section
Biomedical Imaging Technology Study Section (BMIT)
Program Officer
Redmond, George O
Project Start
2017-03-15
Project End
2021-02-27
Budget Start
2017-03-15
Budget End
2018-02-28
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Sri International
Department
Type
DUNS #
009232752
City
Menlo Park
State
CA
Country
United States
Zip Code
94025