This is a competing continuation application. This longitudinal study examines the etiologic determinants of changes between adolescence and adulthood in alcohol and drug use and dependence, and the consequences of alcohol and drug use and abuse/dependence on the individual's functioning. The ultimate goal of this research is to investigate developmental pathways to alcohol and drug use and dependence and cessation, and to identify adult protective factors that will offset risks for alcohol and drug use and dependence in adulthood. The sample includes low-income urban African American and Puerto Rican adults who were seen in early/middle adolescence, then in late adolescence, then in their early 20?s, and again in their mid 20?s. We now propose to study them in their thirties. A fifth data collection is proposed to accomplish the following: (1) examine the interrelations and interactions of risk and protective factors, including personality, family, peers, ecological context, acculturation/cultural values, and African American and Puerto Rican ethnic/racial identity, as they affect the course of alcohol and drug use/abuse/dependence (i.e., onset, stability, cessation) and criminal behavior in these adults;and (2) To study the consequences of early alcohol and drug use and abuse/dependence and other problem behaviors on adult intra- and interpersonal functioning. Interviews with the adult participants will be conducted by trained, interviewers. Scales with adequate psychometric properties measuring the independent variables will be developed from the interview schedules. The primary analytic techniques will be structural equation modeling and other regression-based techniques. This research will enable us to provide further information on (1) suggested specific strategies to prevent increases in alcohol and drug use and dependence, (2) factors promoting the decrease or cessation of drug use, and (3) the timing most adequate to implement these strategies.

Public Health Relevance

The significance of the proposed study lies in its potential to identify important risk and protective factors for alcohol and drug use and dependence and their developmental timing. Thus, knowledge gained from this research will inform both prevention and public policy about the developmental pathways to alcohol and drug use and dependence, and factors related to cessation. In sum, the goals of this study should serve to provide information on specific strategies to prevent increases in alcohol and drug use and dependence, and on how and when these strategies can be most effectively implemented, which is of great relevance to the mission of the National Institute on Drug Abuse.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA005702-21
Application #
8414882
Study Section
Community Influences on Health Behavior (CIHB)
Program Officer
Etz, Kathleen
Project Start
1993-06-01
Project End
2014-12-31
Budget Start
2013-01-01
Budget End
2013-12-31
Support Year
21
Fiscal Year
2013
Total Cost
$585,900
Indirect Cost
$174,869
Name
New York University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Brook, Judith S; Lee, Jung Yeon; Brook, David W (2015) Trajectories of Marijuana Use Beginning in Adolescence Predict Tobacco Dependence in Adulthood. Subst Abus 36:470-7
Pahl, Kerstin; Brook, Judith S; Lee, Jung Yeon (2014) Adolescent self-control predicts joint trajectories of marijuana use and depressive mood into young adulthood among urban African Americans and Puerto Ricans. J Behav Med 37:675-82
Brook, Judith S; Lee, Jung Yeon; Balka, Elinor B et al. (2014) Impact of conjoint trajectories of body mass index and marijuana use on short sleep duration. Am J Addict 23:176-83
Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2014) Developmental trajectories of marijuana use from adolescence to adulthood: relationship with using weapons including guns. Aggress Behav 40:229-37
Brook, Judith S; Lee, Jung Yeon; Rubenstone, Elizabeth et al. (2014) Triple comorbid trajectories of tobacco, alcohol, and marijuana use as predictors of antisocial personality disorder and generalized anxiety disorder among urban adults. Am J Public Health 104:1413-20
Pahl, Kerstin; Brook, Judith S; Lee, Jung Yeon (2013) Joint trajectories of victimization and marijuana use and their health consequences among urban African American and Puerto Rican young men. J Behav Med 36:305-14
Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2013) Adult work commitment, financial stability, and social environment as related to trajectories of marijuana use beginning in adolescence. Subst Abus 34:298-305
Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2013) Physical factors, personal characteristics, and substance use: associations with obesity. Subst Abus 34:273-6
Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2013) Long-term consequences of membership in trajectory groups of delinquent behavior in an urban sample: violence, drug use, interpersonal, and neighborhood attributes. Aggress Behav 39:440-52
Brook, Judith S; Lee, Jung Yeon; Brown, Elaine N et al. (2012) Comorbid trajectories of tobacco and marijuana use as related to psychological outcomes. Subst Abus 33:156-67

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