Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA006486-06
Application #
2118701
Study Section
Special Emphasis Panel (SRCD (21))
Project Start
1990-04-01
Project End
2001-03-31
Budget Start
1996-05-15
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Georgetown University
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Xiao, Yingxian; Abdrakhmanova, Galya R; Baydyuk, Maryna et al. (2009) Rat neuronal nicotinic acetylcholine receptors containing alpha7 subunit: pharmacological properties of ligand binding and function. Acta Pharmacol Sin 30:842-50
Xiao, Yingxian; Kellar, Kenneth J (2004) The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. J Pharmacol Exp Ther 310:98-107
Xiao, Yingxian; Baydyuk, Maryna; Wang, Haizhu Pearl et al. (2004) Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells. Bioorg Med Chem Lett 14:1845-8
Wei, Zhi-Liang; Petukhov, Pavel A; Xiao, Yingxian et al. (2003) Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues. J Med Chem 46:921-4
Davila-Garcia, Martha I; Musachio, John L; Kellar, Kenneth J (2003) Chronic nicotine administration does not increase nicotinic receptors labeled by [125I]epibatidine in adrenal gland, superior cervical ganglia, pineal or retina. J Neurochem 85:1237-46
Avila, Amy M; Davila-Garcia, Martha I; Ascarrunz, Veronica S et al. (2003) Differential regulation of nicotinic acetylcholine receptors in PC12 cells by nicotine and nerve growth factor. Mol Pharmacol 64:974-86
Abdrakhmanova, Galya; Dorfman, Julia; Xiao, Yingxian et al. (2002) Protons enhance the gating kinetics of the alpha3/beta4 neuronal nicotinic acetylcholine receptor by increasing its apparent affinity to agonists. Mol Pharmacol 61:369-78
Meyer, E L; Xiao, Y; Kellar, K J (2001) Agonist regulation of rat alpha 3 beta 4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells. Mol Pharmacol 60:568-76
Xiao, Y; Smith, R D; Caruso, F S et al. (2001) Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs. J Pharmacol Exp Ther 299:366-71
Yeh, J J; Yasuda, R P; Davila-Garcia, M I et al. (2001) Neuronal nicotinic acetylcholine receptor alpha3 subunit protein in rat brain and sympathetic ganglion measured using a subunit-specific antibody: regional and ontogenic expression. J Neurochem 77:336-46

Showing the most recent 10 out of 25 publications