Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA009491-03
Application #
2122770
Study Section
Special Emphasis Panel (SRCD)
Project Start
1994-09-30
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Psychiatry
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Little, Karley Y; Krolewski, David M; Zhang, Lian et al. (2003) Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users. Am J Psychiatry 160:47-55
Little, Karley Y; Elmer, Lawrence W; Zhong, Huailing et al. (2002) Cocaine induction of dopamine transporter trafficking to the plasma membrane. Mol Pharmacol 61:436-45
Little, K Y; Zhang, L; Desmond, T et al. (1999) Striatal dopaminergic abnormalities in human cocaine users. Am J Psychiatry 156:238-45
Lopez, J F; Chalmers, D T; Little, K Y et al. (1998) A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression. Biol Psychiatry 43:547-73
Little, K Y; McLaughlin, D P; Zhang, L et al. (1998) Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. Am J Psychiatry 155:207-13
Little, K Y; Carroll, F I; Butts, J D (1998) Striatal [125I]RTI-55 binding sites in cocaine-abusing humans. Prog Neuropsychopharmacol Biol Psychiatry 22:455-66
Little, K Y; McLaughlin, D P; Zhang, L et al. (1998) Brain dopamine transporter messenger RNA and binding sites in cocaine users: a postmortem study. Arch Gen Psychiatry 55:793-9
Mitsuyama, H; Little, K Y; Sieghart, W et al. (1998) GABA(A) receptor alpha1, alpha4, and beta3 subunit mRNA and protein expression in the frontal cortex of human alcoholics. Alcohol Clin Exp Res 22:815-22
Zhang, L; Elmer, L W; Little, K Y (1998) Expression and regulation of the human dopamine transporter in a neuronal cell line. Brain Res Mol Brain Res 59:66-73
Little, K Y; McLauglin, D P; Ranc, J et al. (1997) Serotonin transporter binding sites and mRNA levels in depressed persons committing suicide. Biol Psychiatry 41:1156-64

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