The revised application proposes a five-year extension of the Early Steps Multisite Project (ES-M) focused on Understanding and Preventing Childhood Drug Use Risk. The ES-M project is a collaboration of the Child and Family Center at the University of Oregon (Dishion), the University of Pittsburgh (Shaw), and the University of Virginia (Wilson). During its first five years the project exceeded expected recruitment rates (731), maintained high retention rates (85%), successfully engaged families in our family-intervention model, and produced reductions in problem behavior and emotion distress in children from ages 2 to 4 years. We have found that improvements in children's adjustment were mediated by improved family management practices. In the next five years we propose to adapt the family intervention model to provide support for each child's transition into the public school system, and conduct developmental analyses to better understand early emergence of school competence, early deviant peer involvement problem behavior, and emotion distress. We will also address the role of siblings in children's development and as an intervention outcome variable. Biannual intensive assessments are proposed that include home visits and direct observations, as well as yearly assessments of the child's problem behavior and self-regulation in the family context. This assessment builds on an existing multiagent-multimethod assessment strategy across all three sites that has included yearly direct observations as well as measurement of child and family characteristics. We propose that the study will test the effectiveness of a feasible, cost-effective, family-centered intervention that can be initiated within WIC or similar service settings and be continued and maintained in the public school environment. In addition, the data set affords a rich opportunity to link caregiver engagement in the intervention with child and family outcomes. The net effect of this family-centered, early intervention strategy is significant reduction of risk for early-onset problem behavior, improved school competence, reduction in children's mental health disorders, and reductions in risk for drug use from age 2 to 10. Advancements in multivariate data analysis such as general growth mixture modeling will be used to study the environmental factors associated with the formation of health and of high-risk developmental trajectories, as well as to determine the effectiveness of the family intervention in altering those trajectories.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Project (R01)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Sims, Belinda E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Oregon
Other Health Professions
Organized Research Units
United States
Zip Code
Leijten, Patty; Shaw, Daniel S; Gardner, Frances et al. (2015) The family check-up and service use in high-risk families of young children: a prevention strategy with a bridge to community-based treatment. Prev Sci 16:397-406
Smith, Justin D; Dishion, Thomas J; Shaw, Daniel S et al. (2015) Negative relational schemas predict the trajectory of coercive dynamics during early childhood. J Abnorm Child Psychol 43:693-703
Waller, Rebecca; Gardner, Frances; Shaw, Daniel S et al. (2015) Callous-unemotional behavior and early-childhood onset of behavior problems: the role of parental harshness and warmth. J Clin Child Adolesc Psychol 44:655-67
Smith, Justin D; Dishion, Thomas J; Shaw, Daniel S et al. (2014) Coercive family process and early-onset conduct problems from age 2 to school entry. Dev Psychopathol 26:917-32
Piehler, Timothy F; Dishion, Thomas J (2014) Dyadic coregulation and deviant talk in adolescent friendships: interaction patterns associated with problematic substance use in early adulthood. Dev Psychol 50:1160-9
Dishion, Thomas J; Kim, Hanjoe; Stormshak, Elizabeth A et al. (2014) A brief measure of peer affiliation and social acceptance (PASA): validity in an ethnically diverse sample of early adolescents. J Clin Child Adolesc Psychol 43:601-12
Waller, Rebecca; Gardner, Frances; Viding, Essi et al. (2014) Bidirectional associations between parental warmth, callous unemotional behavior, and behavior problems in high-risk preschoolers. J Abnorm Child Psychol 42:1275-85
Smith, Justin D; Dishion, Thomas J; Shaw, Daniel S et al. (2013) Indirect effects of fidelity to the family check-up on changes in parenting and early childhood problem behaviors. J Consult Clin Psychol 81:962-74
Brennan, Lauretta M; Shelleby, Elizabeth C; Shaw, Daniel S et al. (2013) Indirect Effects of the Family Check-Up on School-Age Academic Achievement Through Improvements in Parenting in Early Childhood. J Educ Psychol 105:
Hyde, Luke W; Shaw, Daniel S; Gardner, Frances et al. (2013) Dimensions of callousness in early childhood: links to problem behavior and family intervention effectiveness. Dev Psychopathol 25:347-63

Showing the most recent 10 out of 35 publications