Early indicators of risk become increasingly relevant to alcohol and other drug use (substance use;SU) in late adolescence when SU escalates and substance-related problems emerge. Risk for SU builds cumulatively and sequentially over the course of adolescence, and understanding SU in late adolescence requires a characterization of the early adolescent risk context. Behavior problems in early adolescence set the stage for poor adaptation and increased risk for SU with incentive salience and effortful regulation playing an important role in escalation of SU. Yet, most research has focused exclusively on risk conferred by externalizing problems (e.g., aggression and delinquency). The etiological role of internalizing problems (e.g., anxiety and depression), though potentially significant, is poorly understood. No long-term longitudinal studies have followed youth from pre-initiation to use, escalation, and emergence of problems to provide a developmental account of the link between internalizing problems and SU. Moreover, social context (e.g. peers, parents) is a strong influence on adolescent SU, and changes dramatically from early to late adolescence. Limited SU research has focused on individual level changes in internalizing problems within this social context. The proposed project fills these critical gaps in the literature. This is a continuation o a study of SU in a community sample initially assessed at ages 11-13 years. The proposed project will follow the sample into late adolescence for three additional multi-method assessments (mean ages 18, 19, and 20 years) to evaluate continuity and discontinuity in individual and environmental risk over these years. A critical feature of our longitudinal design i the ability to compare directly how the role of internalizing problems, mediation, moderation, and potential bidirectional associations shift across age and stage of use (initiation, heavy use, problem use). The project will examine: 1) The changing role of internalizing problems with age and stage of use;2. Key mediators (motives for SU and peer affiliations) and moderators (peer norms, parent-adolescent relationship quality) of the effects of internalizing;3) Reciprocal associations between incentive salience, effortful regulation, internalizing symptoms, and SU.

Public Health Relevance

Adolescence is a critical period for onset and escalation of substance use (SU).The high personal and societal costs of adolescent SU make it a critical public health problem. Validated and developmentally informed etiological theories are crucial for advancing effective preventive interventions. This project will inform such etiological models, and provide much needed knowledge for the development of interventions.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Project (R01)
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Study Section
Risk, Prevention and Intervention for Addictions Study Section (RPIA)
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Weinberg, Naimah Z
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State University of New York at Buffalo
Schools of Arts and Sciences
United States
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Pardee, Carolyn Speidel; Colder, Craig R; Bowker, Julie C (2014) Dynamic associations among alcohol use and anxiety symptoms in early adolescence. Psychol Addict Behav 28:1246-52
Scalco, Matthew D; Colder, Craig R; Hawk, Larry W et al. (2014) Internalizing and externalizing problem behavior and early adolescent substance use: a test of a latent variable interaction and conditional indirect effects. Psychol Addict Behav 28:828-40
Trucco, Elisa M; Colder, Craig R; Wieczorek, William F et al. (2014) Early adolescent alcohol use in context: how neighborhoods, parents, and peers impact youth. Dev Psychopathol 26:425-36
Trucco, Elisa M; Wright, Aidan G C; Colder, Craig R (2014) Stability and change of social goals in adolescence. J Pers 82:379-89
Lopez-Vergara, Hector I; Colder, Craig R (2013) An examination of the specificity of motivation and executive functioning in ADHD symptom-clusters in adolescence. J Pediatr Psychol 38:1081-90
Colder, Craig R; Hawk Jr, Larry W; Lengua, Liliana J et al. (2013) Trajectories of Reinforcement Sensitivity During Adolescence and Risk for Substance Use. J Res Adolesc 23:345-356
Rhodes, Jessica D; Colder, Craig R; Trucco, Elisa M et al. (2013) The interaction between self-regulation and motivation prospectively predicting problem behavior in adolescence. J Clin Child Adolesc Psychol 42:681-92
Colder, Craig R; Scalco, Matthew; Trucco, Elisa M et al. (2013) Prospective associations of internalizing and externalizing problems and their co-occurrence with early adolescent substance use. J Abnorm Child Psychol 41:667-77
Trucco, Elisa M; Wright, Aidan G C; Colder, Craig R (2013) A revised interpersonal circumplex inventory of children's social goals. Assessment 20:98-113
Zehe, Jennifer M; Colder, Craig R; Read, Jennifer P et al. (2013) Social and generalized anxiety symptoms and alcohol and cigarette use in early adolescence: the moderating role of perceived peer norms. Addict Behav 38:1931-9

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