Early indicators of risk become increasingly relevant to alcohol and other drug use (substance use;SU) in late adolescence when SU escalates and substance-related problems emerge. Risk for SU builds cumulatively and sequentially over the course of adolescence, and understanding SU in late adolescence requires a characterization of the early adolescent risk context. Behavior problems in early adolescence set the stage for poor adaptation and increased risk for SU with incentive salience and effortful regulation playing an important role in escalation of SU. Yet, most research has focused exclusively on risk conferred by externalizing problems (e.g., aggression and delinquency). The etiological role of internalizing problems (e.g., anxiety and depression), though potentially significant, is poorly understood. No long-term longitudinal studies have followed youth from pre-initiation to use, escalation, and emergence of problems to provide a developmental account of the link between internalizing problems and SU. Moreover, social context (e.g. peers, parents) is a strong influence on adolescent SU, and changes dramatically from early to late adolescence. Limited SU research has focused on individual level changes in internalizing problems within this social context. The proposed project fills these critical gaps in the literature. This is a continuation o a study of SU in a community sample initially assessed at ages 11-13 years. The proposed project will follow the sample into late adolescence for three additional multi-method assessments (mean ages 18, 19, and 20 years) to evaluate continuity and discontinuity in individual and environmental risk over these years. A critical feature of our longitudinal design i the ability to compare directly how the role of internalizing problems, mediation, moderation, and potential bidirectional associations shift across age and stage of use (initiation, heavy use, problem use). The project will examine: 1) The changing role of internalizing problems with age and stage of use;2. Key mediators (motives for SU and peer affiliations) and moderators (peer norms, parent-adolescent relationship quality) of the effects of internalizing;3) Reciprocal associations between incentive salience, effortful regulation, internalizing symptoms, and SU.

Public Health Relevance

Adolescence is a critical period for onset and escalation of substance use (SU).The high personal and societal costs of adolescent SU make it a critical public health problem. Validated and developmentally informed etiological theories are crucial for advancing effective preventive interventions. This project will inform such etiological models, and provide much needed knowledge for the development of interventions.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Project (R01)
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Risk, Prevention and Intervention for Addictions Study Section (RPIA)
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Weinberg, Naimah Z
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State University of New York at Buffalo
Schools of Arts and Sciences
United States
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Meisel, Samuel N; Colder, Craig R; Bowker, Julie C et al. (2018) A longitudinal examination of mediational pathways linking chronic victimization and exclusion to adolescent alcohol use. Dev Psychol 54:1795-1807
Colder, Craig R; Frndak, Seth; Lengua, Liliana J et al. (2018) Internalizing and Externalizing Problem Behavior: a Test of a Latent Variable Interaction Predicting a Two-Part Growth Model of Adolescent Substance Use. J Abnorm Child Psychol 46:319-330
Colder, Craig R; Shyhalla, Kathleen; Frndak, Seth E (2018) Early alcohol use with parental permission: Psychosocial characteristics and drinking in late adolescence. Addict Behav 76:82-87
Scalco, Matthew D; Colder, Craig R (2017) Trajectories of marijuana use from late childhood to late adolescence: Can Temperament × Experience interactions discriminate different trajectories of marijuana use? Dev Psychopathol 29:775-790
Colder, Craig R; Shyhalla, Kathleen; Frndak, Seth et al. (2017) The Prospective Association Between Internalizing Symptoms and Adolescent Alcohol Involvement and the Moderating Role of Age and Externalizing Symptoms. Alcohol Clin Exp Res 41:2185-2196
Meisel, Samuel N; Colder, Craig R (2017) Social Goals Impact Adolescent Substance Use through Influencing Adolescents' Connectedness to Their Schools. J Youth Adolesc 46:2015-2027
Scalco, Matthew D; Meisel, Samuel N; Colder, Craig R (2016) Misperception and accurate perception of close friend substance use in early adolescence: Developmental and intervention implications. Psychol Addict Behav 30:300-11
Meisel, Samuel N; Colder, Craig R; Hawk, Larry W (2015) The moderating role of cognitive capacities in the association between social norms and drinking behaviors. Alcohol Clin Exp Res 39:1049-56
Meisel, Samuel N; Colder, Craig R (2015) Social Goals and Grade as Moderators of Social Normative Influences on Adolescent Alcohol Use. Alcohol Clin Exp Res 39:2455-62
Scalco, Matthew D; Trucco, Elisa M; Coffman, Donna L et al. (2015) Selection and Socialization Effects in Early Adolescent Alcohol Use: A Propensity Score Analysis. J Abnorm Child Psychol 43:1131-43

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