This proposal requests continued support for a program of research on young children with severe-to- profound hearing loss. The long-term goal of this project is to investigate the effects of early intervention with cochlear implants (CIs) or hearing aids (HAs) on the development of speech perception, spoken word recognition and language skills longitudinally in children with prelingual hearing loss. We will also investigate variation and individual differences in speech and language outcomes after cochlear implantation. The proposed research is organized into three subprojects. First, we will investigate spoken word recognition and language development during the first three years of life in children with congenital, severe- to-profound hearing loss who have received either CIs or HAs. Second, we will examine spoken word recognition and receptive language abilities as a function of age at time of implantation in children who all are implanted prior to 3 years of age. Third, we will explore the benefits of CIs in children who present with handicapping conditions in addition to hearing loss. The proposed research should provide important new knowledge about the effectiveness of CIs in very young children who are representative of the current population of pediatric Cl recipients - children with severe-to-profound hearing loss identified through universal newborn hearing screening who are implanted prior to age 3 years. Such information will help to inform decisions regarding the medical and audiological management of infants and children with hearing loss. Furthermore, these projects are theoretically important because they examine the consequences of early auditory deprivation and early linguistic experience after implantation on the development of speech perception, spoken word recognition and language abilities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000064-18
Application #
7340119
Study Section
Language and Communication Study Section (LCOM)
Program Officer
Donahue, Amy
Project Start
1990-04-01
Project End
2010-01-31
Budget Start
2008-02-01
Budget End
2010-01-31
Support Year
18
Fiscal Year
2008
Total Cost
$566,638
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
King, Kelly A; Brewer, Carmen C (2018) Clinical trials, ototoxicity grading scales and the audiologist's role in therapeutic decision making. Int J Audiol 57:S89-S98
Lindsey, Spencer; Brewer, Carmen; Stakhovskaya, Olga et al. (2017) Auditory and otologic profile of Alström syndrome: Comprehensive single center data on 38 patients. Am J Med Genet A 173:2210-2218
Brewer, Carmen C; Zalewski, Christopher K; King, Kelly A et al. (2016) Heritability of non-speech auditory processing skills. Eur J Hum Genet 24:1137-44
Anaya, Esperanza M; Pisoni, David B; Kronenberger, William G (2016) Long-term musical experience and auditory and visual perceptual abilities under adverse conditions. J Acoust Soc Am 140:2074
Kronenberger, William G; Pisoni, David B; Harris, Michael S et al. (2013) Profiles of verbal working memory growth predict speech and language development in children with cochlear implants. J Speech Lang Hear Res 56:805-25
Harris, Michael S; Kronenberger, William G; Gao, Sujuan et al. (2013) Verbal short-term memory development and spoken language outcomes in deaf children with cochlear implants. Ear Hear 34:179-92
Kirk, Karen Iler; Prusick, Lindsay; French, Brian et al. (2012) Assessing spoken word recognition in children who are deaf or hard of hearing: a translational approach. J Am Acad Audiol 23:464-75
Houston, Derek M; Beer, Jessica; Bergeson, Tonya R et al. (2012) The ear is connected to the brain: some new directions in the study of children with cochlear implants at Indiana University. J Am Acad Audiol 23:446-63
Beer, Jessica; Harris, Michael S; Kronenberger, William G et al. (2012) Auditory skills, language development, and adaptive behavior of children with cochlear implants and additional disabilities. Int J Audiol 51:491-8
Houston, Derek M; Stewart, Jessica; Moberly, Aaron et al. (2012) Word learning in deaf children with cochlear implants: effects of early auditory experience. Dev Sci 15:448-61

Showing the most recent 10 out of 49 publications