Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
2R01DC001689-05
Application #
2126710
Study Section
Hearing Research Study Section (HAR)
Project Start
1992-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Cotanche, Douglas A; Kaiser, Christina L (2010) Hair cell fate decisions in cochlear development and regeneration. Hear Res 266:18-25
Kaiser, Christina L; Kamien, Andrew J; Shah, Priyanka A et al. (2009) 5-Ethynyl-2'-deoxyuridine labeling detects proliferating cells in the regenerating avian cochlea. Laryngoscope 119:1770-5
Cotanche, Douglas A (2008) Genetic and pharmacological intervention for treatment/prevention of hearing loss. J Commun Disord 41:421-43
Kaiser, Christina L; Chapman, Brittany J; Guidi, Jessica L et al. (2008) Comparison of activated caspase detection methods in the gentamicin-treated chick cochlea. Hear Res 240:1-11
Spencer, Nathaniel J; Cotanche, Douglas A; Klapperich, Catherine M (2008) Peptide- and collagen-based hydrogel substrates for in vitro culture of chick cochleae. Biomaterials 29:1028-42
Parker, Mark A; Corliss, Deborah A; Gray, Brianna et al. (2007) Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells. Hear Res 232:29-43
Dai, C F; Mangiardi, D; Cotanche, D A et al. (2006) Uptake of fluorescent gentamicin by vertebrate sensory cells in vivo. Hear Res 213:64-78
Duncan, Luke J; Mangiardi, Dominic A; Matsui, Jonathan I et al. (2006) Differential expression of unconventional myosins in apoptotic and regenerating chick hair cells confirms two regeneration mechanisms. J Comp Neurol 499:691-701
Morest, D Kent; Cotanche, Douglas A (2004) Regeneration of the inner ear as a model of neural plasticity. J Neurosci Res 78:455-60
Mangiardi, Dominic A; McLaughlin-Williamson, Katherine; May, Kara E et al. (2004) Progression of hair cell ejection and molecular markers of apoptosis in the avian cochlea following gentamicin treatment. J Comp Neurol 475:1-18

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