The proposed research addresses hypotheses concerning the way speech movements are planned and executed. The hypotheses are guided by a computational model of the neural control of speech movements combined with a biomechanically based vocal-tract model. To test these hypotheses, we conduct experiments with speakers and listeners in which we measure articulatory movements, speech acoustics, perception, and brain activation. We manipulate speech condition (e.g., clear vs. fast speech), phonemic context, and speech sound class, and we introduce transient and sustained perturbations. We also perform simulation experiments in which we adapt the vocal-tract model to the morphologies of individual speakers. Movements of this vocal-tract model are commanded by our neural control model for the same utterances and conditions used in our experiments, and the resulting movements and acoustics are compared to those of the modeled speaker, in order to test the model. The research addresses 3 inter-related issues: 1. The nature of phonemic and syllabic goals for articulatory movements. Here we study the effects of speaking conditions and speaker differences on auditory goals for vowels; the effects of speakers' discriminative capacities on the phoneme contrasts they produce; and the effects of auditory and articulatory perturbations on phonemic contrast and their interaction with sound class and speaker acuity. 2. The role of feedback and feedforward mechanisms in the control of speech movements. The performance of these control sub-systems is probed by introducing unpredictable and sustained perturbations. We test model-based hypotheses about changes in brain activation and acoustic and articulatory trajectories elicited by each of these interventions. 3. Movement trajectory planning in the concatenation of phonemes and larger units. In this study we investigate the planning of movements in the concatenation of words. We measure articulatory movements in gestural overlap and their acoustic and perceptual correlates in order to test the hypothesis that such overlap leaves perceptible acoustic cues for listeners. We believe these studies will provide important information regarding the neural control mechanisms underlying speech production. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC001925-14
Application #
7321094
Study Section
Biobehavioral and Behavioral Processes 3 (BBBP)
Program Officer
Shekim, Lana O
Project Start
1993-12-01
Project End
2009-11-30
Budget Start
2007-12-01
Budget End
2009-11-30
Support Year
14
Fiscal Year
2008
Total Cost
$624,819
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Internal Medicine/Medicine
Type
Schools of Arts and Sciences
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Perkell, Joseph S (2013) Five decades of research in speech motor control: what have we learned, and where should we go from here? J Speech Lang Hear Res 56:S1857-74
Perkell, Joseph S (2012) Movement goals and feedback and feedforward control mechanisms in speech production. J Neurolinguistics 25:382-407
Cai, Shanqing; Ghosh, Satrajit S; Guenther, Frank H et al. (2011) Focal manipulations of formant trajectories reveal a role of auditory feedback in the online control of both within-syllable and between-syllable speech timing. J Neurosci 31:16483-90
Cai, Shanqing; Ghosh, Satrajit S; Guenther, Frank H et al. (2010) Adaptive auditory feedback control of the production of formant trajectories in the Mandarin triphthong /iau/ and its pattern of generalization. J Acoust Soc Am 128:2033-48
Ghosh, Satrajit S; Matthies, Melanie L; Maas, Edwin et al. (2010) An investigation of the relation between sibilant production and somatosensory and auditory acuity. J Acoust Soc Am 128:3079-87
Ghosh, Satrajit S; Tourville, Jason A; Guenther, Frank H (2008) A neuroimaging study of premotor lateralization and cerebellar involvement in the production of phonemes and syllables. J Speech Lang Hear Res 51:1183-202
Villacorta, Virgilio M; Perkell, Joseph S; Guenther, Frank H (2007) Sensorimotor adaptation to feedback perturbations of vowel acoustics and its relation to perception. J Acoust Soc Am 122:2306-19
Guenther, Frank H; Ghosh, Satrajit S; Tourville, Jason A (2006) Neural modeling and imaging of the cortical interactions underlying syllable production. Brain Lang 96:280-301
Nieto-Castanon, Alfonso; Guenther, Frank H; Perkell, Joseph S et al. (2005) A modeling investigation of articulatory variability and acoustic stability during American English /r/ production. J Acoust Soc Am 117:3196-212
Perkell, Joseph S; Matthies, Melanie L; Tiede, Mark et al. (2004) The distinctness of speakers' /s/-/S/ contrast is related to their auditory discrimination and use of an articulatory saturation effect. J Speech Lang Hear Res 47:1259-69

Showing the most recent 10 out of 19 publications